Property Summary

NCBI Gene PubMed Count 13
PubMed Score 8.03
PubTator Score 7.05

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (14)

Disease log2 FC p
hepatocellular carcinoma 1.100 1.4e-04
malignant mesothelioma -1.600 2.5e-06
astrocytic glioma -1.100 1.4e-02
ependymoma 1.300 1.6e-02
psoriasis -1.900 1.2e-04
osteosarcoma 1.940 1.7e-05
atypical teratoid / rhabdoid tumor -1.400 4.4e-06
glioblastoma -1.700 9.2e-04
medulloblastoma, large-cell -1.600 2.8e-06
lung cancer 1.400 8.0e-03
pediatric high grade glioma -1.400 1.6e-04
group 4 medulloblastoma 1.100 4.6e-04
Pick disease 1.200 2.0e-04
ovarian cancer 1.300 1.1e-04

 GWAS Trait (1)

Gene RIF (1)

PMID Text
16901896 SNAP50 zinc finger domain contributes to cooperative promoter recognition by human SNAPC

AA Sequence

MAEGSRGGPTCSGVGGRQDPVSGSGGCNFPEYELPELNTRAFHVGAFGELWRGRLRGAGDLSLREPPASA      1 - 70
LPGSQAADSDREDAAVARDLDCSLEAAAELRAVCGLDKLKCLEDGEDPEVIPENTDLVTLGVRKRFLEHR     71 - 140
EETITIDRACRQETFVYEMESHAIGKKPENSADMIEEGELILSVNILYPVIFHKHKEHKPYQTMLVLGSQ    141 - 210
KLTQLRDSIRCVSDLQIGGEFSNTPDQAPEHISKDLYKSAFFYFEGTFYNDKRYPECRDLSRTIIEWSES    211 - 280
HDRGYGKFQTARMEDFTFNDLCIKLGFPYLYCHQGDCEHVIVITDIRLVHHDDCLDRTLYPLLIKKHWLW    281 - 350
TRKCFVCKMYTARWVTNNDSFAPEDPCFFCDVCFRMLHYDSEGNKLGEFLAYPYVDPGTFN             351 - 411
//

Text Mined References (14)

PMID Year Title
25416956 2014 A proteome-scale map of the human interactome network.
17525332 2007 ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
17474147 2007 Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.
16901896 2006 The unorthodox SNAP50 zinc finger domain contributes to cooperative promoter recognition by human SNAPC.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15164053 2004 DNA sequence and analysis of human chromosome 9.
12621023 2003 The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
11094070 2000 The retinoblastoma tumor suppressor protein targets distinct general transcription factors to regulate RNA polymerase III gene expression.
11056176 2001 A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc.
9003788 1996 Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc.
8816454 1996 Cloning and characterization of the beta subunit of human proximal sequence element-binding transcription factor and its involvement in transcription of small nuclear RNA genes by RNA polymerases II and III.
7715707 1995 A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III.
900378 1977 [Diagnostic importance of determining 17-ketosteroids in gynecology].