Tbio SMIM1 Small integral membrane protein 1

Protein Summary

Description

Regulator of red blood cell formation. This gene encodes a small, conserved protein that participates in red blood cell formation. The encoded protein is localized to the cell membrane and is the antigen for the Vel blood group. Alternative splicing results in different transcript variants that encode the same protein. [provided by RefSeq, Dec 2013]

Uniprot Accession IDs

• B2RUZ4

Gene Name

• SMIM1

Ensembl ID

• ENST00000444870
• ENSP00000457386
• ENSG00000235169

Symbol

• Vel

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue sample	0.8
cell type or tissue	0.49
tissue	0.47
cell line	0.43
biological term	0.33

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 41.46   (req: < 5)

Gene RIFs: 12   (req: <= 3)

Antibodies: 29   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 41.46   (req: >= 5)

Gene RIFs: 12   (req: > 3)

Antibodies: 29   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0