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Tchem
SLC5A4
Solute carrier family 5 member 4

Protein Summary
Description
Has electrogenic activity in response to glucose, and may function as a glucose sensor (PubMed:13130073, PubMed:17110502, PubMed:20421923, PubMed:22766068). Mediates influx of sodium ions into the cell but does not transport sugars (PubMed:13130073, PubMed:22766068). Also potently activated by imino sugars such as deoxynojirimycin (DNJ) (PubMed:17110502, PubMed:20421923, PubMed:22766068).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000266086
  • ENSP00000266086
  • ENSG00000100191

Symbol
  • SAAT1
  • SGLT3
  • SAAT1
  • SGLT3
  • DJ90G24.4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.6
cell type or tissue
0.56
pathway
0.52
cell line
0.5
metabolite
0.45


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2369.26   (req: < 5)
Gene RIFs: 10   (req: <= 3)
Antibodies: 99   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2369.26   (req: >= 5)
Gene RIFs: 10   (req: > 3)
Antibodies: 99   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 28
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drugs: 2