| Tdark | Putative sodium-coupled neutral amino acid transporter 10 |
Putative sodium-dependent amino acid/proton antiporter.
Comments
| Disease | Target Count | P-value |
|---|---|---|
| non-small cell lung cancer | 2798 | 6.2e-16 |
| Breast cancer | 3098 | 5.9e-10 |
| malignant mesothelioma | 3163 | 5.1e-06 |
| atypical teratoid / rhabdoid tumor | 4369 | 8.8e-06 |
| pediatric high grade glioma | 2712 | 1.5e-05 |
| psoriasis | 6685 | 2.2e-05 |
| tuberculosis | 1563 | 3.4e-05 |
| ovarian cancer | 8491 | 8.2e-05 |
| glioblastoma | 5572 | 1.5e-04 |
| medulloblastoma, large-cell | 6234 | 6.6e-04 |
| astrocytoma | 1493 | 1.1e-03 |
| ependymoma | 2514 | 1.5e-02 |
| Disease | log2 FC | p |
|---|---|---|
| malignant mesothelioma | -1.200 | 5.1e-06 |
| ependymoma | 1.300 | 1.5e-02 |
| psoriasis | 2.900 | 2.2e-05 |
| astrocytoma | 1.800 | 1.1e-03 |
| atypical teratoid / rhabdoid tumor | 1.100 | 8.8e-06 |
| glioblastoma | 1.200 | 1.5e-04 |
| medulloblastoma, large-cell | 1.200 | 6.6e-04 |
| tuberculosis | 1.400 | 3.4e-05 |
| non-small cell lung cancer | 1.132 | 6.2e-16 |
| pediatric high grade glioma | 1.100 | 1.5e-05 |
| Breast cancer | 1.300 | 5.9e-10 |
| ovarian cancer | 1.500 | 8.2e-05 |
MTAAAASNWGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYA 1 - 70 GLAFHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGFQVGGTFRMFLLFAVSLCIVLPL 71 - 140 SLQRNMMASIQSFSAMALLFYTVFMFVIVLSSLKHGLFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQ 141 - 210 VLPTYDSLDEPSVKTMSSIFASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHFPSNLVTEMLRVGFMMS 211 - 280 VAVGFPMMILPCRQALSTLLCEQQQKDGTFAAGGYMPPLRFKALTLSVVFGTMVGGILIPNVETILGLTG 281 - 350 ATMGSLICFICPALIYKKIHKNALSSQVVLWVGLGVLVVSTVTTLSVSEEVPEDLAEEAPGGRLGEAEGL 351 - 420 MKVEAARLSAQDPVVAVAEDGREKPKLPKEREELEQAQIKGPVDVPGREDGKEAPEEAQLDRPGQGIAVP 421 - 490 VGEAHRHEPPVPHDKVVVDEGQDREVPEENKPPSRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKR 491 - 560 PGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKGGP 561 - 630 PPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLEEAGRAEMLDHAV 631 - 700 LLQVIKEQQVQQKRLLDQQEKLLAVIEEQHKEIHQQRQEDEEDKPRQVEVHQEPGAAVPRGQEAPEGKAR 701 - 770 ETVENLPPLPLDPVLRAPGGRPAPSQDLNQRSLEHSEGPVGRDPAGPPDGGPDTEPRAAQAKLRDGQKDA 771 - 840 APRAAGTVKELPKGPEQVPVPDPAREAGGPEERLAEEFPGQSQDVTGGSQDRKKPGKEVAATGTSILKEA 841 - 910 NWLVAGPGAETGDPRMKPKQVSRDLGLAADLPGGAEGAAAQPQAVLRQPELRVISDGEQGGQQGHRLDHG 911 - 980 GHLEMRKARGGDHVPVSHEQPRGGEDAAVQEPRQRPEPELGLKRAVPGGQRPDNAKPNRDLKLQAGSDLR 981 - 1050 RRRRDLGPHAEGQLAPRDGVIIGLNPLPDVQVNDLRGALDAQLRQAAGGALQVVHSRQLRQAPGPPEES 1051 - 1119 //
| PMID | Year | Title | |
|---|---|---|---|
| 24275569 | 2014 | An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. | |
| 23506890 | Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects. | ||
| 23382691 | 2013 | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | |
| 20834067 | 2010 | Joint influence of small-effect genetic variants on human longevity. | |
| 16625196 | 2006 | DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. | |
| 15498874 | 2004 | Large-scale cDNA transfection screening for genes related to cancer development and progression. | |
| 15489334 | 2004 | The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). | |
| 14702039 | 2004 | Complete sequencing and characterization of 21,243 full-length human cDNAs. | |
| 12477932 | 2002 | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |
