| Tbio | High affinity copper uptake protein 1 |
High-affinity, saturable copper transporter involved in dietary copper uptake.
The protein encoded by this gene is a high-affinity copper transporter found in the cell membrane. The encoded protein functions as a homotrimer to effect the uptake of dietary copper. [provided by RefSeq, Aug 2011]
The protein encoded by this gene is a high-affinity copper transporter found in the cell membrane. The encoded protein functions as a homotrimer to effect the uptake of dietary copper. [provided by RefSeq, Aug 2011]
Comments
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Congenital Abnormalities | 11 | 0.0 | 0.0 |
| Embryo Loss | 7 | 0.0 | 0.0 |
| Hypertension, Pulmonary | 37 | 0.0 | 0.0 |
| Intellectual disability | 1016 | 0.0 | 0.0 |
| Liver Neoplasms, Experimental | 59 | 0.0 | 0.0 |
| Manganese Poisoning | 11 | 0.0 | 0.0 |
| Necrosis | 53 | 0.0 | 0.0 |
| Prostatic Neoplasms | 495 | 0.0 | 0.0 |
| Disease | Target Count |
|---|---|
| Congenital Abnormality | 11 |
| Pulmonary hypertension | 85 |
| Disease | Target Count | P-value |
|---|---|---|
| ovarian cancer | 8520 | 5.4e-06 |
| pancreatic ductal adenocarcinoma liver metastasis | 1962 | 7.1e-04 |
| pancreatic carcinoma | 562 | 3.8e-03 |
| pancreatic cancer | 2398 | 3.8e-03 |
| glioblastoma | 5792 | 4.6e-03 |
| subependymal giant cell astrocytoma | 2287 | 3.4e-02 |
| Disease | log2 FC | p |
|---|---|---|
| glioblastoma | 1.200 | 4.6e-03 |
| ovarian cancer | 2.400 | 5.4e-06 |
| pancreatic cancer | 1.100 | 3.8e-03 |
| pancreatic carcinoma | 1.100 | 3.8e-03 |
| pancreatic ductal adenocarcinoma liver m... | -1.752 | 7.1e-04 |
| subependymal giant cell astrocytoma | 1.111 | 3.4e-02 |
| Species | Source | Disease |
|---|---|---|
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid EggNOG | ||
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid EggNOG |
