| Tbio | SLC2A4 regulator |
Transcription factor involved in SLC2A4 and HD gene transactivation. Binds to the consensus sequence 5'-GCCGGCG-3'.
The protein encoded by this gene is a nuclear transcription factor involved in the activation of the solute carrier family 2 member 4 gene. The encoded protein interacts with another transcription factor, myocyte enhancer factor 2, to activate transcription of this gene. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a nuclear transcription factor involved in the activation of the solute carrier family 2 member 4 gene. The encoded protein interacts with another transcription factor, myocyte enhancer factor 2, to activate transcription of this gene. [provided by RefSeq, Jul 2008]
Comments
| Disease | Target Count | P-value |
|---|---|---|
| Breast cancer | 3578 | 7.5e-13 |
| ependymoma | 4679 | 4.8e-08 |
| osteosarcoma | 7950 | 1.8e-07 |
| atypical teratoid / rhabdoid tumor | 5112 | 4.4e-07 |
| psoriasis | 6694 | 3.7e-05 |
| malignant mesothelioma | 3232 | 6.8e-05 |
| glioblastoma | 5792 | 8.5e-05 |
| tuberculosis | 2010 | 8.7e-05 |
| pediatric high grade glioma | 1064 | 8.8e-05 |
| dermatomyositis | 966 | 4.0e-03 |
| Disease | log2 FC | p |
|---|---|---|
| atypical teratoid / rhabdoid tumor | 1.600 | 4.4e-07 |
| Breast cancer | 1.600 | 7.5e-13 |
| dermatomyositis | -1.200 | 4.0e-03 |
| ependymoma | 1.600 | 4.8e-08 |
| glioblastoma | 1.800 | 8.5e-05 |
| malignant mesothelioma | 1.200 | 6.8e-05 |
| osteosarcoma | -3.624 | 1.8e-07 |
| pediatric high grade glioma | 1.300 | 8.8e-05 |
| psoriasis | -1.300 | 3.7e-05 |
| tuberculosis | 1.100 | 8.7e-05 |
MERPPPRAAGRDPSALRAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQESEPRASDLGA 1 - 70 PRTWTGAAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTSPLLLGAPVAAFSPEPGLEPWKEA 71 - 140 LVRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPPLPPEAAHFLFGEPTLRKRKSPAQVMFQCLWKSCGKV 141 - 210 LSTASAMQRHIRLVHLGRQAEPEQSDGEEDFYYTELDVGVDTLTDGLSSLTPVSPTASMPPAFPRLELPE 211 - 280 LLEPPALPSPLRPPAPPLPPPPVLSTVANPQSCHSDRVYQGCLTPARLEPQPTEVGACPPALSSRIGVTL 281 - 350 RKPRGDAKKCRKVYGMERRDLWCTACRWKKACQRFLD 351 - 387 //
