Property Summary

NCBI Gene PubMed Count 21
PubMed Score 15.85
PubTator Score 25.33

Knowledge Summary


No data available



 GWAS Trait (1)

Protein-protein Interaction (7)

Gene RIF (5)

25797253 the SLC25A10 carrier plays an important role in regulating redox homeostasis to protect confluent cells against oxidative stress.
23266187 Compares and contrasts all the known human SLC25A* genes and includes functional information.
21555518 SLC25A10 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells.
20877624 Observational study of gene-disease association. (HuGE Navigator)
16027120 Slc25a10 plays an important role in supplying malate for citrate transport required for fatty acid synthesis and its inhibition might effectively reduce lipid accumulation in adipose tissues

AA Sequence

FGIKVPS                                                                   281 - 287

Text Mined References (22)

PMID Year Title
26871637 2016 Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
25797253 2015 The mitochondrial carrier SLC25A10 regulates cancer cell growth.
25416956 2014 A proteome-scale map of the human interactome network.
23266187 The mitochondrial transporter family SLC25: identification, properties and physiopathology.
23259602 2012 Genome-wide association scan of dental caries in the permanent dentition.
21630459 2011 Proteomic characterization of the human sperm nucleus.
21555518 2011 The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle.
21516116 2011 Next-generation sequencing to generate interactome datasets.
21437236 2011 A20 modulates lipid metabolism and energy production to promote liver regeneration.
21269460 2011 Initial characterization of the human central proteome.
20949348 2011 The dicarboxylate carrier plays a role in mitochondrial malate transport and in the regulation of glucose-stimulated insulin secretion from rat pancreatic beta cells.
20877624 2010 Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
19447967 2009 Shifted Transversal Design smart-pooling for high coverage interactome mapping.
19060904 2009 An empirical framework for binary interactome mapping.
18029348 2008 Toward a confocal subcellular atlas of the human proteome.
16303743 2005 Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.
16189514 2005 Towards a proteome-scale map of the human protein-protein interaction network.
16027120 2005 Identification of dicarboxylate carrier Slc25a10 as malate transporter in de novo fatty acid synthesis.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
10585886 1999 Organization and sequence of the gene for the human mitochondrial dicarboxylate carrier: evolution of the carrier family.
10072589 1998 Assignment of the human dicarboxylate carrier gene (DIC) to chromosome 17 band 17q25.3.