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Tbio
SLC1A4
Neutral amino acid transporter A

Protein Summary
Description
Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence. The protein encoded by this gene is a sodium-dependent neutral amino acid transporter for alanine, serine, cysteine, and threonine. Defects in this gene have been associated with developmental delay, microcephaly, and intellectual disability. [provided by RefSeq, Jan 2017]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000234256
  • ENSP00000234256
  • ENSG00000115902
  • ENST00000531327
  • ENSP00000431942

Symbol
  • ASCT1
  • SATT
  • SATT
  • ASCT1
  • SPATCCM
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
1
molecular function
1
transcription factor perturbation
0.98
kinase perturbation
0.97
virus perturbation
0.96


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 121.99   (req: < 5)
Gene RIFs: 14   (req: <= 3)
Antibodies: 222   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 121.99   (req: >= 5)
Gene RIFs: 14   (req: > 3)
Antibodies: 222   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 20
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0