| Tbio | Vesicular glutamate transporter 2 |
Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.
Comments
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Learning Disorders | 29 | 0.0 | 0.0 |
| Memory Disorders | 40 | 0.0 | 0.0 |
| Disease | Target Count |
|---|---|
| Schizophrenia | 1160 |
| Bipolar Disorder | 666 |
| Major Depressive Disorder | 301 |
| Unipolar Depression | 250 |
| Disease | Target Count | P-value |
|---|---|---|
| lung carcinoma | 2843 | 8.9e-16 |
| ovarian cancer | 8520 | 1.7e-08 |
| Astrocytoma, Pilocytic | 3081 | 6.1e-08 |
| glioblastoma | 5792 | 1.7e-05 |
| osteosarcoma | 7950 | 1.5e-03 |
| atypical teratoid / rhabdoid tumor | 5112 | 6.3e-03 |
| astrocytic glioma | 2597 | 8.0e-03 |
| ependymoma | 4679 | 9.0e-03 |
| oligodendroglioma | 2850 | 1.7e-02 |
| non primary Sjogren syndrome sicca | 891 | 3.0e-02 |
| adult high grade glioma | 3801 | 4.1e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Blue color blindness | 3 | 3.743 | 1.9 |
| Parkinson's disease | 392 | 3.721 | 1.9 |
| REM sleep behavior disorder | 14 | 3.41 | 1.7 |
| Disease | log2 FC | p |
|---|---|---|
| adult high grade glioma | -2.600 | 4.1e-02 |
| astrocytic glioma | -3.600 | 8.0e-03 |
| Astrocytoma, Pilocytic | -4.800 | 6.1e-08 |
| atypical teratoid / rhabdoid tumor | -3.000 | 6.3e-03 |
| ependymoma | -4.300 | 9.0e-03 |
| glioblastoma | -3.500 | 1.7e-05 |
| lung carcinoma | 3.700 | 8.9e-16 |
| non primary Sjogren syndrome sicca | -1.200 | 3.0e-02 |
| oligodendroglioma | -3.500 | 1.7e-02 |
| osteosarcoma | -1.264 | 1.5e-03 |
| ovarian cancer | -1.500 | 1.7e-08 |
| Species | Source | Disease |
|---|---|---|
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA | ||
| Inparanoid OMA | ||
| Inparanoid OMA EggNOG |
MESVKQRILAPGKEGLKNFAGKSLGQIYRVLEKKQDTGETIELTEDGKPLEVPERKAPLCDCTCFGLPRR 1 - 70 YIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNWDPETVGMIHGSFFWGYIITQI 71 - 140 PGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLE 141 - 210 RSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGSFGMVWYMFWLLVSYESPAKHPTITDEERR 211 - 280 YIEESIGESANLLGAMEKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGM 281 - 350 LSAVPHLVMTIIVPIGGQIADFLRSKQILSTTTVRKIMNCGGFGMEATLLLVVGYSHTRGVAISFLVLAV 351 - 420 GFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKNKSREEWQYVFLIAALVHYGG 421 - 490 VIFYAIFASGEKQPWADPEETSEEKCGFIHEDELDEETGDITQNYINYGTTKSYGATTQANGGWPSGWEK 491 - 560 KEEFVQGEVQDSHSYKDRVDYS 561 - 582 //
