SLC16A4
Monocarboxylate transporter 5
Protein Summary
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).
- ENST00000369779
- ENSP00000358794
- ENSG00000168679
- ENST00000369781
- ENSP00000358796
- ENST00000437429
- ENSP00000394790
- ENST00000472422
- ENSP00000432495
- ENST00000541986
- ENSP00000446087
- MCT4
- MCT5
- MCT4
- MCT5
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
gene perturbation | 0.97 | ||
cell type or tissue | 0.8 | ||
PubMedID | 0.59 | ||
tissue | 0.59 | ||
tissue sample | 0.59 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 313.86 (req: < 5)
Gene RIFs: 102 (req: <= 3)
Antibodies: 108 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 313.86 (req: >= 5)
Gene RIFs: 102 (req: > 3)
Antibodies: 108 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0