Tbio SLC13A4 Solute carrier family 13 member 4

Protein Summary

Description

Sodium/sulfate cotransporter that mediates sulfate reabsorption in the high endothelial venules (HEV).

Uniprot Accession IDs

• Q9UKG4
• A4D1Q4
• Q8N631

Gene Name

• SLC13A4

Ensembl ID

• ENST00000354042
• ENSP00000297282
• ENSG00000164707

Symbol

• SUT1
• NAS2
• SUT1
• SUT-1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.76
gene perturbation	0.65
tissue	0.52
cell line	0.49
PubMedID	0.49

Protein Classes

PANTHER Classes

Protein / Transporter / Cation Transporter / Solute Carrier Family 13 Member 4

DTO Classes

Protein / Transporter / Slc Superfamily Of Solute Carriers / Slc13 Family Of Sodium-dependent Sulphate/carboxylate Transporters / Solute Carrier Family 13 Member 4

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 71.52   (req: < 5)

Gene RIFs: 6   (req: <= 3)

Antibodies: 79   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 71.52   (req: >= 5)

Gene RIFs: 6   (req: > 3)

Antibodies: 79   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0