| Tbio | SERTA domain-containing protein 1 |
Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.
Comments
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Colonic Neoplasms | 142 | 0.0 | 0.0 |
| Disease | Target Count |
|---|---|
| Mood Disorders | 184 |
| Disease | Target Count | P-value |
|---|---|---|
| non-small cell lung cancer | 2890 | 2.2e-18 |
| primary pancreatic ductal adenocarcinoma | 1109 | 4.3e-04 |
| ovarian cancer | 8520 | 6.2e-04 |
| pancreatic cancer | 2398 | 7.6e-04 |
| medulloblastoma, large-cell | 6241 | 4.3e-03 |
| tuberculosis | 2010 | 8.6e-03 |
| group 3 medulloblastoma | 4104 | 1.2e-02 |
| invasive ductal carcinoma | 2951 | 1.4e-02 |
| Disease | log2 FC | p |
|---|---|---|
| group 3 medulloblastoma | -1.300 | 1.2e-02 |
| invasive ductal carcinoma | -1.192 | 1.4e-02 |
| medulloblastoma, large-cell | -1.200 | 4.3e-03 |
| non-small cell lung cancer | -1.677 | 2.2e-18 |
| ovarian cancer | 1.200 | 6.2e-04 |
| pancreatic cancer | 1.900 | 7.6e-04 |
| primary pancreatic ductal adenocarcinoma | 1.774 | 4.3e-04 |
| tuberculosis | -1.100 | 8.6e-03 |
