Tbio SCGB2A1 Mammaglobin-B

Protein Summary

Description

May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones.

Uniprot Accession IDs

• O75556

Gene Name

• SCGB2A1

Ensembl ID

• ENST00000244930
• ENSP00000244930
• ENSG00000124939

Symbol

• LIPHC
• MGB2
• UGB3
• LPHC
• LPNC
• MGB2
• UGB3

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell type or tissue	0.56
small molecule perturbation	0.54
disease	0.48
chemical	0.44
biological term	0.42

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 71.36   (req: < 5)

Gene RIFs: 17   (req: <= 3)

Antibodies: 170   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 71.36   (req: >= 5)

Gene RIFs: 17   (req: > 3)

Antibodies: 170   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0