Tchem SBK1 Serine/threonine-protein kinase SBK1

Protein Summary

Description

May be involved in signal-transduction pathways related to the control of brain development.

Uniprot Accession IDs

• Q52WX2

Gene Name

• SBK1

Ensembl ID

• ENST00000341901
• ENSP00000343248
• ENSG00000188322

Symbol

• SBK

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.9
protein domain	0.73
histone modification site profile	0.69
transcription factor binding site profile	0.57
PubMedID	0.56

Protein Classes

PANTHER Classes

Protein / Transferase / Kinase / Protein Kinase / Serine/threonine-protein Kinase Sbk1

DTO Classes

Protein / Kinase / Protein Kinase / Other Group / Nkf1 Family / Serine/threonine-protein Kinase Sbk1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 31.18   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 20   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 31.18   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 20   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 2

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0