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Tbio Receptor-transporting protein 2

Specifically promotes functional cell surface expression of olfactory receptors, but not of other GPCRs.

 Comments

Property Summary

NCBI Gene PubMed Count 8
PubMed Score 6.86
PubTator Score 3.37

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (1)

Disease Target Count Z-score Confidence
Parathyroid carcinoma 5 4.158 2.1

Expression

Synonym

Accession Q5QGT7 Q6NVH4
Symbols Z3CXXC2

Gene

RTP2

  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG

 UniProt Keyword (7)

 GO Function (1)

 GO Component (4)

 GO Process (3)

 Compartment GO Term (10)

 MGI Phenotype (1)

 HCA RNA Cell Line (9)

Pathway (4)

AA Sequence 

MCTSLTTCEWKKVFYEKMEVAKPADSWELIIDPNLKPSELAPGWKQYLEQHASGRFHCSWCWHTWQSAHV      1 - 70
VILFHMFLDRAQRAGSVRMRVFKQLCYECGTARLDESSMLEENIEGLVDNLITSLREQCYEEDGGQYRIH     71 - 140
VASRPDSGPHRAEFCEACQEGIVHWKPSEKLLEEEVTTYTSEASKPRAQAGSGYNFLSLRWCLFWASLCL    141 - 210
LVVYLQFSFLSPAFF                                                           211 - 225
//

Text Mined References (8)

PMID Year Title
25416956 2014 A proteome-scale map of the human interactome network.
23284291 2012 Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.
17207965 2007 hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.
16720576 2006 Members of RTP and REEP gene families influence functional bitter taste receptor expression.
16271481 2005 Inherited ACTH insensitivity illuminates the mechanisms of ACTH action.
15550249 2004 RTP family members induce functional expression of mammalian odorant receptors.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.