Tdark RTBDN Retbindin

Protein Summary

Description

Riboflavin-binding protein which might have a role in retinal flavin transport. This gene was first identified in a study of human eye tissues. The protein encoded by this gene is preferentially expressed in the retina and may play a role in binding retinoids and other carotenoids as it shares homology with riboflavin binding proteins. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]

Uniprot Accession IDs

• Q9BSG5
• F1T0I8
• Q9BWT5

Gene Name

• RTBDN

Ensembl ID

• ENST00000322912
• ENSP00000326253
• ENSG00000132026
• ENST00000393233
• ENSP00000376925
• ENST00000458671
• ENSP00000416375
• ENST00000592204
• ENSP00000466765

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell type or tissue	0.76
kinase perturbation	0.76
transcription factor	0.6
cell line	0.56
chemical	0.43

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.71   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 40   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.71   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 40   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0