Tbio RRP36 Ribosomal RNA processing protein 36 homolog

Protein Summary

Description

Involved in the early processing steps of the pre-rRNA in the maturation pathway leading to the 18S rRNA. RRP36 functions at an early stage in the processing of 35S preribosomal RNA into the mature 18S species (Gerus et al., 2010 [PubMed 20038530]).[supplied by OMIM, Jul 2010]

Uniprot Accession IDs

• Q96EU6
• Q9BRF6
• Q9P0C8

Gene Name

• RRP36

Ensembl ID

• ENST00000244496
• ENSP00000244496
• ENSG00000124541

Symbol

• C6orf153
• C6orf153
• dJ20C7.4

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.66
cellular component	0.57
cell type or tissue	0.56
tissue	0.56
histone modification site profile	0.55

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.04   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 71   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.04   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 71   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0