| Tdark | 60S ribosomal protein L3-like |
This gene encodes a protein that shares sequence similarity with ribosomal protein L3. The protein belongs to the L3P family of ribosomal proteins. Unlike the ubiquitous expression of ribosomal protein genes, this gene has a tissue-specific pattern of expression, with the highest levels of expression in skeletal muscle and heart. It is not currently known whether the encoded protein is a functional ribosomal protein or whether it has evolved a function that is independent of the ribosome. [provided by RefSeq, Jul 2008]
Comments
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Neoplasm Invasiveness | 161 | 0.0 | 0.0 |
| Disease | Target Count | P-value |
|---|---|---|
| Duchenne muscular dystrophy | 601 | 5.6e-10 |
| acute quadriplegic myopathy | 1158 | 3.2e-06 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Polycystic kidney disease 1 | 21 | 3.481 | 1.7 |
| Disease | log2 FC | p |
|---|---|---|
| acute quadriplegic myopathy | -1.659 | 3.2e-06 |
| Duchenne muscular dystrophy | -1.368 | 5.6e-10 |
MSHRKFSAPRHGHLGFLPHKRSHRHRGKVKTWPRDDPSQPVHLTAFLGYKAGMTHTLREVHRPGLKISKR 1 - 70 EEVEAVTIVETPPLVVVGVVGYVATPRGLRSFKTIFAEHLSDECRRRFYKDWHKSKKKAFTKACKRWRDT 71 - 140 DGKKQLQKDFAAMKKYCKVIRVIVHTQMKLLPFRQKKAHIMEIQLNGGTVAEKVAWAQARLEKQVPVHSV 141 - 210 FSQSEVIDVIAVTKGRGVKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPARVGCSIARAGQKGYHHRTEL 211 - 280 NKKIFRIGRGPHMEDGKLVKNNASTSYDVTAKSITPLGGFPHYGEVNNDFVMLKGCIAGTKKRVITLRKS 281 - 350 LLVHHSRQAVENIELKFIDTTSKFGHGRFQTAQEKRAFMGPQKKHLEKETPETSGDL 351 - 407 //
