Property Summary

NCBI Gene PubMed Count 13
PubMed Score 22.11
PubTator Score 16.75

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (17)

Disease log2 FC p
astrocytic glioma 1.900 3.2e-03
ependymoma 2.100 2.4e-03
oligodendroglioma 2.100 3.0e-03
psoriasis -3.600 2.5e-05
osteosarcoma -4.634 1.6e-13
cystic fibrosis -1.229 2.9e-04
primitive neuroectodermal tumor 1.300 5.8e-03
pancreatic ductal adenocarcinoma liver m... -1.004 2.3e-02
intraductal papillary-mucinous adenoma (... 1.300 2.0e-03
intraductal papillary-mucinous carcinoma... 1.700 5.2e-03
lung cancer 2.400 5.8e-05
Breast cancer 2.000 3.8e-02
group 3 medulloblastoma 1.300 2.7e-02
Pick disease -1.400 1.3e-05
progressive supranuclear palsy -1.200 1.7e-02
ovarian cancer -2.100 1.4e-11
pituitary cancer -1.300 6.5e-04

Gene RIF (5)

PMID Text
23010595 hRIPalpha is involved in cell proliferation through regulation of RPA transport
21360055 The results show that DDX3, eIF5A, and hRIP enhance HIV-1 internal ribosomal entry site-mediated translation.
20237496 Observational study of gene-disease association. (HuGE Navigator)
19336370 Observational study of gene-disease association. (HuGE Navigator)
16135809 hRIPbeta localises to the PML nuclear body and transports replication protein A (PML) into the PML nuclear body and releases RPA upon UV irradiation.

AA Sequence

MAESLRSPRRSLYKLVGSPPWKEAFRQRCLERMRNSRDRLLNRYRQAGSSGPGNSQNSFLVQEVMEEEWN      1 - 70
ALQSVENCPEDLAQLEELIDMAVLEEIQQELIKQEQSIISEYEKSLQFDEKCLSIMLAEWEANPLICPVC     71 - 140
TKYNLRITSGVVVCQCGLSIPSHSSELTEQKLRACLEGSINEHSAHCPHTPEFSVTGGTEEKSSLLMSCL    141 - 210
ACDTWAVIL                                                                 211 - 219
//

Text Mined References (16)

PMID Year Title
23186163 2013 Toward a comprehensive characterization of a human cancer cell phosphoproteome.
23010595 2012 Elevated level of human RPA interacting protein ? (hRIP?) in cervical tumor cells is involved in cell proliferation through regulating RPA transport.
21360055 2011 Translational regulation of HIV-1 replication by HIV-1 Rev cellular cofactors Sam68, eIF5A, hRIP, and DDX3.
20237496 2010 New genetic associations detected in a host response study to hepatitis B vaccine.
19413330 2009 Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
19336370 2009 Determination of genetic predisposition to patent ductus arteriosus in preterm infants.
18029348 2008 Toward a confocal subcellular atlas of the human proteome.
17207965 2007 hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.
16625196 2006 DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
16344560 2006 Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
16135809 2005 Sumoylation of the novel protein hRIP{beta} is involved in replication protein A deposition in PML nuclear bodies.
16008515 2005 Identification, expression pattern, and subcellular location of human RIP isoforms.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
8125298 1994 Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.