Protein Summary
Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation.
- ENST00000251776
- ENSP00000251776
- ENSG00000114547
- ENST00000505382
- ENSP00000421662
- ENST00000511082
- ENSP00000424447
- ENST00000514116
- ENSP00000426271
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
tissue sample | 0.68 | ||
cell line | 0.52 | ||
tissue | 0.44 | ||
biological process | 0.42 | ||
cell type or tissue | 0.41 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.67 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 76 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.67 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 76 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 14
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0