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Tbio
RMDN3
Regulator of microtubule dynamics protein 3

Protein Summary
Description
Involved in cellular calcium homeostasis regulation. May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000260385
  • ENSP00000260385
  • ENSG00000137824
  • ENST00000338376
  • ENSP00000342493

Symbol
  • FAM82A2
  • FAM82C
  • PTPIP51
  • RMD3
  • RMD-3
  • FAM82C
  • FAM82A2
  • ptpip51
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
1
transcription factor perturbation
0.96
cell type or tissue
0.73
transcription factor binding site profile
0.69
co-expressed gene
0.65


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 39.16   (req: < 5)
Gene RIFs: 18   (req: <= 3)
Antibodies: 170   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 39.16   (req: >= 5)
Gene RIFs: 18   (req: > 3)
Antibodies: 170   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0