Property Summary

NCBI Gene PubMed Count 8
PubMed Score 5.89
PubTator Score 5.62

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (10)

Disease log2 FC p
posterior fossa group B ependymoma -2.400 2.9e-14
glioblastoma -1.900 7.5e-04
medulloblastoma -1.700 2.6e-06
atypical teratoid / rhabdoid tumor -2.300 9.9e-09
medulloblastoma, large-cell -2.100 6.3e-05
primitive neuroectodermal tumor -1.500 1.4e-03
adult high grade glioma -2.100 6.8e-05
pilocytic astrocytoma -2.000 2.2e-08
pituitary cancer 1.300 3.0e-05
psoriasis -1.900 1.6e-26

Synonym

Accession Q9H426 A4FU94 E1P613 Q3MI44 Q5JWT7
Symbols RIM4
RIM 4
RIM-4
C20orf190
RIM4gamma
RIM4-gamma

Gene

PANTHER Protein Class (2)

  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG

Gene RIF (2)

PMID Text
20379614 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
18187620 Knockdown of regulating synaptic membrane exocytosis 4 (RIMS4) by siRNA inhibits HIV-1 replication in HeLa-derived TZM-bl cells

AA Sequence

MERSQSRLSLSASFEALAIYFPCMNSFDDEDAGDSRRLKGAIQRSTETGLAVEMPSRTLRQASHESIEDS      1 - 70
MNSYGSEGNLNYGGVCLASDAQFSDFLGSMGPAQFVGRQTLATTPMGDVEIGLQERNGQLEVDIIQARGL     71 - 140
TAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLFPESPQGKVLQVIVWGNYGRMERK    141 - 210
QFMGVARVLLEELDLTTLAVGWYKLFPTSSMVDPATGPLLRQASQLSLESTVGPCGERS               211 - 269
//

Text Mined References (9)

PMID Year Title
23251661 2012 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
20379614 Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
17525332 2007 ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15217342 2004 The synaptic vesicle cycle.
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12620390 2003 Genomic definition of RIM proteins: evolutionary amplification of a family of synaptic regulatory proteins.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
11780052 2001 The DNA sequence and comparative analysis of human chromosome 20.