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Tbio Raftlin

May play a pivotal role in the formation and/or maintenance of lipid rafts. May regulate B-cell antigen receptor-mediated signaling.

 Comments

Property Summary

NCBI Gene PubMed Count 16
PubMed Score 5.50
PubTator Score 6.70

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (4)

Disease Target Count Z-score Confidence
Carcinoma 11493 0.0 0.8
Disease Target Count Z-score Confidence
Eye and adnexa disease 18 0.0 2.4
Obesity 678 0.0 1.0
Disease Target Count Z-score Confidence
Glaucoma 239 3.24 1.6

Expression

  Differential Expression (27)

Disease log2 FC p
adrenocortical carcinoma -1.177 1.9e-02
atypical teratoid / rhabdoid tumor -1.100 4.7e-02
Breast cancer 1.700 1.6e-07
chronic lymphosyte leukemia -1.500 1.9e-06
cystic fibrosis 1.100 3.8e-04
ductal carcinoma in situ -1.100 2.4e-02
fibroadenoma -1.700 2.1e-02
gastric carcinoma 1.800 1.3e-02
group 4 medulloblastoma -1.700 7.1e-03
interstitial cystitis 1.600 7.3e-04
intraductal papillary-mucinous adenoma (... -2.000 6.5e-03
intraductal papillary-mucinous carcinoma... -2.200 6.8e-03
invasive ductal carcinoma -1.500 9.2e-03
lung adenocarcinoma -1.100 1.6e-05
lung cancer -1.400 5.1e-05
lung carcinoma -1.300 3.3e-19
malignant mesothelioma -1.500 3.2e-07
medulloblastoma, large-cell -2.400 3.9e-05
non-small cell lung cancer -1.406 4.9e-17
ovarian cancer -2.500 8.8e-06
pancreatic cancer 2.600 3.1e-04
primary pancreatic ductal adenocarcinoma 2.697 8.5e-05
primary Sjogren syndrome 1.900 1.4e-04
sarcoidosis -1.100 1.5e-05
subependymal giant cell astrocytoma 1.739 2.4e-02
ulcerative colitis 2.900 9.1e-06
Waldenstrons macroglobulinemia -1.824 3.4e-02

Synonym

Accession Q14699 Q0D2G0 Q496Y2 Q4QQI7 Q5JB48 Q7Z7P2
Symbols MIG2
PIG9
PIB10
RAFTLIN

Gene

RFTN1

  Ortholog (12)

Species Source Disease
Inparanoid OMA EggNOG
OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA
OMA EggNOG

 UniProt Keyword (9)

 GO Function (1)

 GO Component (6)

 GO Process (11)

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 Compartment GO Term (26)

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 MGI Phenotype (2)

 GWAS Trait (4)

 HCA RNA Cell Line (56)

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Protein-protein Interaction (2)

RABGAP1L   ATG2A  

Gene RIF (7)

AA Sequence 

MGCGLNKLEKRDEKRPGNIYSTLKRPQVETKIDVSYEYRFLEFTTLSAAELPGSSAVRLASLRDLPAQLL      1 - 70
ELYQQGFSLAALHPFVQPTHEREKTPLEHIFRAILIKKTDRSQKTDLHNEGYILELDCCSSLDHPTDQKL     71 - 140
IPEFIKKIQEAASQGLKFVGVIPQYHSSVNSAGSSAPVSTANSTEDARDAKNARGDHASLENEKPGTGDV    141 - 210
CSAPAGRNQSPEPSSGPRGEVPLAKQPSSPSGEGDGGELSPQGVSKTLDGPESNPLEVHEEPLSGKMEIF    211 - 280
TLFNKPKSHQKCRQYYPVTIPLHVSKNGQTVSGLDANWLEHMSDHFRKGGMLVNAVFYLGIVNDSLHGLT    281 - 350
DGVFIFEAVSTEDSKTIQGYDAIVVEQWTVLEGVEVQTDYVPLLNSLAAYGWQLTCVLPTPVVKTTSEGS    351 - 420
VSTKQIVFLQRPCLPQKIKKKESKFQWRFSREEMHNRQMRKSKGKLSARDKQQAEENEKNLEDQSSKAGD    421 - 490
MGNCVSGQQQEGGVSEEMKGPVQEDKGEQLSPGGLLCGVGVEGEAVQNGPASHSRALVGICTGHSNPGED    491 - 560
ARDGDAEEVRELGTVEEN                                                        561 - 578
//

Text Mined References (21)

PMID Year Title