Tbio REP15 Rab15 effector protein

Protein Summary

Description

Regulates transferrin receptor recycling from the endocytic recycling compartment. The protein encoded by this intronless gene interacts with GTP-bound Rab15 and is involved in recycling of transferrin receptor from the endocytic recycling compartment to the cell surface. [provided by RefSeq, Sep 2016]

Uniprot Accession IDs

• Q6BDI9
• B2RU16

Gene Name

• REP15

Ensembl ID

• ENST00000310791
• ENSP00000310335
• ENSG00000174236

Symbol

• RAB15EP

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue sample	0.75
cell type or tissue	0.67
cell line	0.6
tissue	0.51
metabolite	0.45

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.57   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 25   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.57   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 25   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0