| Tdark | RCC1-like G exchanging factor-like protein |
This gene encodes a protein containing regulator of chromosome condensation 1-like repeats. The encoded protein may function as a guanine nucleotide exchange factor. This gene is located in a region of chromosome 7 that is deleted in Williams-Beuren syndrome, a multisystem developmental disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Comments
| Disease | Target Count | P-value |
|---|---|---|
| osteosarcoma | 7950 | 1.6e-07 |
| psoriasis | 6694 | 1.5e-04 |
| tuberculosis and treatment for 3 months | 179 | 1.6e-03 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Williams-Beuren syndrome | 50 | 5.302 | 2.7 |
| Disease | log2 FC | p |
|---|---|---|
| osteosarcoma | 1.781 | 1.6e-07 |
| psoriasis | 1.500 | 1.5e-04 |
| tuberculosis and treatment for 3 months | 1.100 | 1.6e-03 |
MALVALVAGARLGRRLSGPGLGRGHWTAARRSRSRREAAEAEAEVPVVQYVGERAARADRVFVWGFSFSG 1 - 70 ALGVPSFVVPSSGPGPRAGARPRRRIQPVPYRLELDQKISSAACGYGFTLLSSKTADVTKVWGMGLNKDS 71 - 140 QLGFHRSRKDKTRGYEYVLEPSPVSLPLDRPQETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKV 141 - 210 VENEIYSESHRVHRMQDFDGQVVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDL 211 - 280 AGVNVIQVATYGDCCLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAV 281 - 350 LNGEGHVFVWGYGILGKGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWGK 351 - 420 NIRGCLGIGRLEDQYFPWRVTMPGEPVDVACGVDHMVTLAKSFI 421 - 464 //
