Tbio RASSF9 Ras association domain-containing protein 9

Protein Summary

Description

May play a role in regulating vesicuar trafficking in cells. The protein encoded by this gene localizes to perinuclear endosomes. This protein associates with peptidylglycine alpha-amidating monooxygenase, and may be involved with the trafficking of this enzyme through secretory or endosomal pathways. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• O75901
• B3KMQ4
• Q8N5U8

Gene Name

• RASSF9

Ensembl ID

• ENST00000361228
• ENSP00000354884
• ENSG00000198774

Symbol

• PAMCI
• PCIP1
• PAMCI
• PCIP1
• P-CIP1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.9
cellular component	0.7
cell type or tissue	0.61
gene perturbation	0.59
tissue sample	0.55

Protein Classes

PANTHER Classes

Protein / Membrane Traffic Protein / Ras Association Domain-containing Protein 9

DTO Classes

Protein / Transporter / Ras Association Domain-containing Protein 9

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 105   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 105   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0