Property Summary

NCBI Gene PubMed Count 26
PubMed Score 32.88
PubTator Score 24.07

Knowledge Summary


No data available


  Differential Expression (7)

Disease log2 FC p
ependymoma -1.100 1.3e-12
group 4 medulloblastoma -1.700 6.2e-10
atypical teratoid / rhabdoid tumor -1.500 8.4e-11
medulloblastoma, large-cell -1.900 5.7e-07
primitive neuroectodermal tumor -1.500 8.9e-07
adult high grade glioma -1.200 2.4e-06
pilocytic astrocytoma -1.100 4.6e-09

Gene RIF (8)

24591568 FIP5-T276 phosphorylation occurs specifically during metaphase and anaphase.
21969467 FIP5-SNX18 complex plays a pivotal role in the polarized transport of apical proteins during apical lumen initiation in epithelial cells.
20877624 Observational study of gene-disease association. (HuGE Navigator)
20717956 These data introduce Rab11b as a crucial regulator and Rip11 as mediator of acidosis-induced V-ATPase traffic in duct cells of submandibular gland.
20379614 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
18957512 Rip11/FIP5-kinesin-II complex plays a key role in the routing of internalized receptors through the perinuclear recycling endosomes.
18384058 analysis of the rearrangement breakpoints suggests that the reciprocal translocation may have formed secondary to incorrect repair of double strand breaks (DSBs) by nonhomologous end-joining (NHEJ).
17854769 These data therefore show that (i) Rab11a regulates cell surface abundance of both GLUT4 and FAT/CD36.

AA Sequence

DRLLVRIMETSPTLLQIPPGPPK                                                   631 - 653

Text Mined References (32)

PMID Year Title
26496610 2015 A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
24591568 2014 FIP5 phosphorylation during mitosis regulates apical trafficking and lumenogenesis.
24275569 2014 An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
24040321 2013 The rab11 effector protein FIP1 regulates adiponectin trafficking and secretion.
23186163 2013 Toward a comprehensive characterization of a human cancer cell phosphoproteome.
21969467 2011 Interaction between FIP5 and SNX18 regulates epithelial lumen formation.
20877624 2010 Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
20717956 2011 Rab11b and its effector Rip11 regulate the acidosis-induced traffic of V-ATPase in salivary ducts.
20379614 Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
20068231 2010 Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
19690332 2009 Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
19413330 2009 Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
18957512 2008 The Rip11/Rab11-FIP5 and kinesin II complex regulates endocytic protein recycling.
18669648 2008 A quantitative atlas of mitotic phosphorylation.
18384058 2008 A de novo apparently balanced translocation [46,XY,t(2;9)(p13;p24)] interrupting RAB11FIP5 identifies a potential candidate gene for autism spectrum disorder.
18029348 2008 Toward a confocal subcellular atlas of the human proteome.
17854769 2007 FIP2 and Rip11 specify Rab11a-mediated cellular distribution of GLUT4 and FAT/CD36 in H9c2-hIR cells.
17081983 2006 Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
16751776 2006 A germline-specific class of small RNAs binds mammalian Piwi proteins.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15324660 2004 Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.
15144186 2004 Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12684040 2003 Gaf-1b is an alternative splice variant of Gaf-1/Rip11.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
12470645 2002 Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and its overexpression condenses the Rab11 positive compartment in HeLa cells.
11495908 2001 Identification and characterization of a family of Rab11-interacting proteins.
11481332 2001 Identification of a novel Rab11/25 binding domain present in Eferin and Rip proteins.
11278501 2001 Gaf-1, a gamma -SNAP-binding protein associated with the mitochondria.
11163216 2000 A Rab11/Rip11 protein complex regulates apical membrane trafficking via recycling endosomes.
10545525 1999 Defining a novel 75-kDa phosphoprotein associated with SS-A/Ro and identification of distinct human autoantibodies.
10048485 1998 Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.