Property Summary

NCBI Gene PubMed Count 13
Grant Count 3
Funding $75,316.8
PubMed Score 28.32
PubTator Score 247.65

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (5)

Disease log2 FC p
osteosarcoma -1.073 0.005
group 4 medulloblastoma -1.900 0.000
medulloblastoma, large-cell -1.900 0.001
pituitary cancer 2.200 0.000
facioscapulohumeral dystrophy 2.100 0.006

Synonym

Accession Q9Y5K3 A8IX00 B2RCX8 B4DK10 E9PD84 O60621 Q86XC9
Symbols CTB
CCTB

Gene

PANTHER Protein Class (2)

Protein-protein Interaction (4)

Gene RIF (5)

PMID Text
26165797 CCT contributes to phospholipid compositional homeostasis. [Review]
25452470 PCYT1B, a placental-specific enzyme post-translationally modifying neurokinin B, is essential for the pathogenic role of CRP in preeclampsia through activation of the neurokinin 3 receptor.
20628086 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
19913121 Observational study of gene-disease association. (HuGE Navigator)
19595683 Human phosphate cytidylyltransferase 1, choline, beta is a novel CaOx crystal growth inhibitor.

AA Sequence

MPVVTTDAESETGIPKSLSNEPPSETMEEIEHTCPQPRLTLTAPAPFADETNCQCQAPHEKLTIAQARLG      1 - 70
TPADRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNEAERYEALRHCR     71 - 140
YVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTSDIITRIV    141 - 210
RDYDVYARRNLQRGYTAKELNVSFINEKRYRFQNQVDKMKEKVKNVEERSKEFVNRVEEKSHDLIQKWEE    211 - 280
KSREFIGNFLELFGPDGAWKQMFQERSSRMLQALSPKQSPVSSPTRSRSPSRSPSPTFSWLPLKTSPPSS    281 - 350
PKAASASISSMSEGDEDEK                                                       351 - 369
//

Publication (15)

PMID Year Title
26165797 2015 CTP:phosphocholine cytidylyltransferase: Function, regulation, and structure of an amphitropic enzyme required for membrane biogenesis.
25452470 2015 Neurokinin 3 receptor and phosphocholine transferase: missing factors for pathogenesis of C-reactive protein in preeclampsia.
21406692 2011 System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
20628086 2010 Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
19913121 2009 Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
19595683 2009 Mass spectrometric identification of human phosphate cytidylyltransferase 1 as a novel calcium oxalate crystal growth inhibitor purified from human renal stone matrix.
15772651 2005 The DNA sequence of the human X chromosome.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15345747 2004 Phosphoproteomic analysis of the developing mouse brain.
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
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