Property Summary

NCBI Gene PubMed Count 13
PubMed Score 2.34
PubTator Score 1.03

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (1)

Disease Target Count P-value
lung cancer 4473 3.09260014027644E-5
colon cancer 1475 1.02133343361703E-4
psoriasis 6685 2.50221591368343E-4
Multiple myeloma 1328 4.92523504897452E-4
dermatomyositis 967 0.00423072463886498
invasive ductal carcinoma 2950 0.00465985617841574
ovarian cancer 8492 0.0165569144796938
Waldenstrons macroglobulinemia 765 0.0277832719849459

Expression

  Differential Expression (8)

Disease log2 FC p
Waldenstrons macroglobulinemia 1.273 0.028
Multiple myeloma 1.667 0.000
psoriasis 1.400 0.000
colon cancer 1.400 0.000
lung cancer 1.700 0.000
invasive ductal carcinoma 1.200 0.005
ovarian cancer 1.400 0.017
dermatomyositis 1.300 0.004

Synonym

Accession Q9Y5J1 Q9H4N6
Symbols WDR50
CGI-48

Gene

  Ortholog (15)

 GO Function (1)

AA Sequence

MPPERRRRMKLDRRTGAKPKRKPGMRPDWKAGAGPGGPPQKPAPSSQRKPPARPSAAAAAIAVAAAEEER      1 - 70
RLRQRNRLRLEEDKPAVERCLEELVFGDVENDEDALLRRLRGPRVQEHEDSGDSEVENEAKGNFPPQKKP     71 - 140
VWVDEEDEDEEMVDMMNNRFRKDMMKNASESKLSKDNLKKRLKEEFQHAMGGVPAWAETTKRKTSSDDES    141 - 210
EEDEDDLLQRTGNFISTSTSLPRGILKMKNCQHANAERPTVARISSVQFHPGAQIVMVAGLDNAVSLFQV    211 - 280
DGKTNPKIQSIYLERFPIFKACFSANGEEVLATSTHSKVLYVYDMLAGKLIPVHQVRGLKEKIVRSFEVS    281 - 350
PDGSFLLINGIAGYLHLLAMKTKELIGSMKINGRVAASTFSSDSKKVYASSGDGEVYVWDVNSRKCLNRF    351 - 420
VDEGSLYGLSIATSRNGQYVACGSNCGVVNIYNQDSCLQETNPKPIKAIMNLVTGVTSLTFNPTTEILAI    421 - 490
ASEKMKEAVRLVHLPSCTVFSNFPVIKNKNISHVHTMDFSPRSGYFALGNEKGKALMYRLHHYSDF        491 - 556
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Text Mined References (22)

PMID Year Title
24275569 2014 An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
23186163 2013 Toward a comprehensive characterization of a human cancer cell phosphoproteome.
22681889 2012 The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
22658674 2012 Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
21406692 2011 System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
20068231 2010 Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
19690332 2009 Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
19413330 2009 Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
19367720 2008 Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.
18669648 2008 A quantitative atlas of mitotic phosphorylation.
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