Tbio ZNF711 Zinc finger protein 711

Protein Summary

Description

Transcription regulator required for brain development. Probably acts as a transcription factor that binds to the promoter of target genes and recruits PHF8 histone demethylase, leading to activate expression of genes involved in neuron development, such as KDM5C. This gene encodes a zinc finger protein of unknown function. It bears similarity to a zinc finger protein which acts as a transcriptional activator. This gene lies in a region of the X chromosome which has been associated with cognitive disability. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q9Y462
• B4DSV4
• Q6NX42
• Q9Y4J6

Gene Name

• ZNF711

Ensembl ID

• ENST00000276123
• ENSP00000276123
• ENSG00000147180
• ENST00000360700
• ENSP00000353922
• ENST00000373165
• ENSP00000362260

Symbol

• CMPX1
• ZNF6
• ZNF4
• ZNF5
• ZNF6
• CMPX1
• MRX97
• Zfp711
• dJ75N13.1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
microRNA	0.76
gene perturbation	0.66
cell type or tissue	0.61
protein domain	0.58
PubMedID	0.58

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 23.8   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 45   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 23.8   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 45   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0