Property Summary

NCBI Gene PubMed Count 17
Grant Count 79
R01 Count 63
Funding $5,722,003.45
PubMed Score 215.00
PubTator Score 4.89

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (2)

Disease log2 FC p
progressive supranuclear palsy -1.200 0.006
ovarian cancer -1.200 0.000

Synonym

Accession Q9Y3D8 A8MSZ6 Q5F2S9 AK6
Symbols CIP
CINAP
AD-004
hCINAP
CGI-137

Gene

AK6

PDB

1RKB   3IIJ   3IIK   3IIL   3IIM   5JZV  

Gene RIF (2)

PMID Text
16079131 hCINAP is a novel coilin-interacting protein encoded by a transcript from the transcription factor TAFIID32 locus
15213396 purification and X ray crystal structure

AA Sequence

MLLPNILLTGTPGVGKTTLGKELASKSGLKYINVGDLAREEQLYDGYDEEYDCPILDEDRVVDELDNQMR      1 - 70
EGGVIVDYHGCDFFPERWFHIVFVLRTDTNVLYERLETRGYNEKKLTDNIQCEIFQVLYEEATASYKEEI     71 - 140
VHQLPSNKPEELENNVDQILKWIEQWIKDHNS                                          141 - 172
//

Text Mined References (17)

PMID Year Title
25416956 2014 A proteome-scale map of the human interactome network.
23246961 2014 hCINAP is a novel regulator of ribosomal protein-HDM2-p53 pathway by controlling NEDDylation of ribosomal protein S14.
22038794 2012 hCINAP is an atypical mammalian nuclear adenylate kinase with an ATPase motif: structural and functional studies.
21269460 2011 Initial characterization of the human central proteome.
20974138 2010 The nuclear ATPase/adenylate kinase hCINAP is recruited to perinucleolar caps generated upon RNA pol.II inhibition.
20186459 2010 Depletion of hCINAP by RNA interference causes defects in Cajal body formation, histone transcription, and cell viability.
19946888 2010 Defining the membrane proteome of NK cells.
16079131 2005 Characterization of hCINAP, a novel coilin-interacting protein encoded by a transcript from the transcription factor TAFIID32 locus.
15630091 2005 The crystal structure of human adenylate kinase 6: An adenylate kinase localized to the cell nucleus.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
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