Property Summary

NCBI Gene PubMed Count 18
PubMed Score 4.69
PubTator Score 6.87

Knowledge Summary


No data available


  Disease Sources (2)

Disease Target Count P-value
osteosarcoma 7933 1.65625834328882E-6
ovarian cancer 8492 4.94334659540809E-4
psoriasis 6685 7.7662324639691E-4
pancreatic ductal adenocarcinoma liver metastasis 1795 0.00244254175247936
Disease Target Count Z-score Confidence
Xeroderma pigmentosum 41 3.789 1.9


  Differential Expression (4)

Disease log2 FC p
psoriasis 1.800 0.001
osteosarcoma 1.964 0.000
pancreatic ductal adenocarcinoma liver m... -1.297 0.002
ovarian cancer 1.500 0.000


Accession Q9Y3D0
Symbols CIA2B


  Ortholog (12)

Species Source
Chimp OMA EggNOG
Macaque OMA EggNOG Inparanoid
Mouse OMA EggNOG Inparanoid
Rat OMA EggNOG Inparanoid
Cow OMA EggNOG Inparanoid
Opossum EggNOG Inparanoid
Chicken OMA EggNOG Inparanoid
Anole lizard OMA EggNOG Inparanoid
Xenopus OMA EggNOG Inparanoid
C. elegans OMA EggNOG Inparanoid
S.cerevisiae EggNOG Inparanoid

Gene RIF (5)

24041693 Co-localization experiments by fluorescent confocal microscopy revealed that FAM96B colocalized with prelamin A in HEK-293 cells.
23891004 CIA2B-CIA1-MMS19 and CIA2A-CIA1 assist different branches of Fe/S protein assembly and intimately link this process to cellular iron regulation via IRP1 Fe/S cluster maturation and IRP2 stabilization.
23150669 The mammalian proteins MMS19, MIP18, and ANT2 are involved in cytoplasmic iron-sulfur cluster protein assembly.
22190034 HIV-1 Tat is identified to have a physical interaction with family with sequence similarity 96, member B (FAM96B) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses
21722264 these findings suggest that FAM96B acts as a regulator of E2-2 through the control of its protein expression.

AA Sequence

RVAAALENTHLLEVVNQCLSARS                                                   141 - 163

Text Mined References (21)

PMID Year Title
25416956 2014 A proteome-scale map of the human interactome network.
24275569 2014 An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
24041693 2013 Identification of FAM96B as a novel prelamin A binding partner.
23891004 2013 Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins.
23150669 2012 The mammalian proteins MMS19, MIP18, and ANT2 are involved in cytoplasmic iron-sulfur cluster protein assembly.
22814378 2012 N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
22678362 2012 MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity.
22678361 2012 MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA metabolism.
21722264 2011 Interference of E2-2-mediated effect in endothelial cells by FAM96B through its limited expression of E2-2.
21516116 2011 Next-generation sequencing to generate interactome datasets.