Property Summary

NCBI Gene PubMed Count 14
PubMed Score 14.63
PubTator Score 4.12

Knowledge Summary


No data available


  Disease Sources (1)

Disease Target Count P-value
osteosarcoma 7933 3.26773963706695E-8
ovarian cancer 8492 8.18471195073937E-7
hepatocellular carcinoma 550 1.92190042529119E-6
tuberculosis and treatment for 6 months 686 4.73484117566618E-6
psoriasis 6685 6.38012668302973E-5
medulloblastoma, large-cell 6234 9.66008809098807E-5
atypical teratoid / rhabdoid tumor 4369 1.38648610817531E-4
oligodendroglioma 2849 7.42383948877386E-4
intraductal papillary-mucinous adenoma (IPMA) 2956 7.43557425292326E-4
pancreatic ductal adenocarcinoma liver metastasis 1795 0.00118454031595946
intraductal papillary-mucinous carcinoma (IPMC) 2988 0.00240766318816171
pancreatic cancer 2300 0.00255104687149265
pancreatic carcinoma 567 0.00255104687149265
group 4 medulloblastoma 1875 0.00292659598285224
ependymoma 2514 0.00541148774796971
glioblastoma 5572 0.00749191422273143
astrocytic glioma 2241 0.00941255238332201
intraductal papillary-mucinous neoplasm (IPMN) 3289 0.0223497400623197



Accession Q9Y3C7 B2R4L9
Symbols Soh1


  Ortholog (9)

Gene RIF (3)

24969180 Results show that miR-1 is downregulated in osteosarcoma cells but both of its targets Med1 and Med31 were overexpressed suggesting that MiR-1 plays an important role on the proliferation of osteosarcoma cells through regulation of Med1 and Med31.
18976975 Knockdown of MED31 by siRNAs inhibits HIV LTR-beta-gal activation in the Tat transactivation assay
18976975 Knockdown of mediator complex subunit 31 (MED31) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells

AA Sequence


Text Mined References (19)

PMID Year Title
24969180 2014 MicroRNA-1 functions as a potential tumor suppressor in osteosarcoma by targeting Med1 and Med31.
22814378 2012 N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
21269460 2011 Initial characterization of the human central proteome.
18691976 2008 Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
16169070 2005 A human protein-protein interaction network: a resource for annotating the proteome.
15989967 2005 MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15383276 2004 A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.
15175163 2004 A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology.
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.