You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
TMED5
Transmembrane emp24 domain-containing protein 5

Protein Summary
Description
Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly. Probably not required for COPI-vesicle-mediated retrograde transport.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000370282
  • ENSP00000359305
  • ENSG00000117500
  • ENST00000479918
  • ENSP00000418992

Symbol
  • p28
  • p24g2
  • CGI-100
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.96
microRNA
0.92
virus perturbation
0.88
transcription factor binding site profile
0.8
histone modification site profile
0.61


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.17   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 32   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.17   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 32   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0