Tbio | MOB-like protein phocein |
May play a role in membrane trafficking, specifically in membrane budding reactions.
This gene was identified based on its similarity with the mouse counterpart. Studies of the mouse counterpart suggest that the expression of this gene may be regulated during oocyte maturation and preimplantation following zygotic gene activation. Alternatively spliced transcript variants encoding distinct isoforms have been observed. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HSPE1.[provided by RefSeq, Feb 2011]
This gene was identified based on its similarity with the mouse counterpart. Studies of the mouse counterpart suggest that the expression of this gene may be regulated during oocyte maturation and preimplantation following zygotic gene activation. Alternatively spliced transcript variants encoding distinct isoforms have been observed. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HSPE1.[provided by RefSeq, Feb 2011]
Comments
Disease | Target Count | P-value |
---|---|---|
tuberculosis and treatment for 6 months | 686 | 4.57809132140019E-6 |
astrocytoma | 1493 | 0.00354259590610375 |
Disease | log2 FC | p |
---|---|---|
astrocytoma | -1.300 | 0.004 |
tuberculosis and treatment for 6 months | 1.200 | 0.000 |
Species | Source |
---|---|
Mouse | EggNOG Inparanoid |
Pig | EggNOG Inparanoid |
Chicken | EggNOG Inparanoid |
Xenopus | EggNOG Inparanoid |
Zebrafish | EggNOG Inparanoid |
PMID | Year | Title |
---|---|---|
26496610 | 2015 | A human interactome in three quantitative dimensions organized by stoichiometries and abundances. |
24872389 | 2014 | hMOB3 modulates MST1 apoptotic signaling and supports tumor growth in glioblastoma multiforme. |
24366813 | 2013 | Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1. |
24255178 | 2013 | Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. |
23455922 | 2013 | Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. |
22814378 | 2012 | N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. |
21269460 | 2011 | Initial characterization of the human central proteome. |
19156129 | 2009 | An integrated workflow for charting the human interaction proteome: insights into the PP2A system. |
18782753 | 2009 | A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein. |
18362890 | 2008 | Threonine 74 of MOB1 is a putative key phosphorylation site by MST2 to form the scaffold to activate nuclear Dbf2-related kinase 1. |
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