Tbio CNPY2 Protein canopy homolog 2

Protein Summary

Description

Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation.

Uniprot Accession IDs

• Q9Y2B0
• B2R7B9
• Q9UHE9

Gene Name

• CNPY2

Ensembl ID

• ENST00000273308
• ENSP00000273308
• ENSG00000257727

Symbol

• MSAP
• TMEM4
• ZSIG9
• MSAP
• TMEM4
• ZSIG9
• HP10390

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease perturbation	1
virus perturbation	0.98
transcription factor perturbation	0.97
histone modification site profile	0.9
kinase perturbation	0.71

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.02   (req: < 5)

Gene RIFs: 15   (req: <= 3)

Antibodies: 158   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.02   (req: >= 5)

Gene RIFs: 15   (req: > 3)

Antibodies: 158   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0