Property Summary

NCBI Gene PubMed Count 10
PubMed Score 47.82
PubTator Score 9.14

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (2)

Disease Target Count P-value
ovarian cancer 8492 1.66426234898398E-12
posterior fossa group B ependymoma 1530 5.86267208827251E-7
Pick disease 1893 2.12994021458593E-5
interstitial cystitis 2299 8.19471294489947E-4
atypical teratoid/rhabdoid tumor 1095 0.00117904706360957
progressive supranuclear palsy 674 0.00760877123889153
chronic rhinosinusitis 512 0.0119586911182515
cystic fibrosis and chronic rhinosinusitis 213 0.0141905331349869
Alzheimer's disease 644 0.0235555518871833
Disease Target Count Z-score Confidence
Beta thalassemia 19 3.152 1.6
Polydactyly 93 3.019 1.5

Expression

  Differential Expression (9)

Synonym

Accession Q9ULD6 A1L4N5 D6RAE6 D6RBT4 Q4W5I8 Q86V55
Symbols INT
PDZD6
PDZK6

Gene

  Ortholog (12)

Species Source
Chimp OMA EggNOG
Macaque OMA Inparanoid
Mouse OMA EggNOG Inparanoid
Dog OMA EggNOG Inparanoid
Horse OMA EggNOG Inparanoid
Cow OMA EggNOG Inparanoid
Pig OMA EggNOG
Opossum OMA EggNOG Inparanoid
Chicken OMA EggNOG Inparanoid
Anole lizard OMA EggNOG Inparanoid
Xenopus OMA EggNOG Inparanoid
Fruitfly OMA Inparanoid

AA Sequence

MASVASCDSRPSSDELPGDPSSQEEDEDYDFEDRVSDSGSYSSASSDYDDLEPEWLDSVQKNGELFYLEL      1 - 70
SEDEEESLLPETPTVNHVRFSENEIIIEDDYKERKKYEPKLKQFTKILRRKRLLPKRCNKKNSNDNGPVS     71 - 140
ILKHQSNQKTGVIVQQRYKDVNVYVNPKKLTVIKAKEQLKLLEVLVGIIHQTKWSWRRTGKQGDGERLVV    141 - 210
HGLLPGGSAMKSGQVLIGDVLVAVNDVDVTTENIERVLSCIPGPMQVKLTFENAYDVKRETSHPRQKKTQ    211 - 280
SNTSDLVKLLWGEEVEGIQQSGLNTPHIIMYLTLQLDSETSKEEQEILYHYPMSEASQKLKSVRGIFLTL    281 - 350
CDMLENVTGTQVTSSSLLLNGKQIHVAYWKESDKLLLIGLPAEEVPLPRLRNMIENVIQTLKFMYGSLDS    351 - 420
AFCQIENVPRLDHFFNLFFQRALQPAKLHSSASPSAQQYDASSAVLLDNLPGVRWLTLPLEIKMELDMAL    421 - 490
SDLEAADFAELSEDYYDMRRLYTILGSSLFYKGYLICSHLPKDDLIDIAVYCRHYCLLPLAAKQRIGQLI    491 - 560
IWREVFPQHHLRPLADSSTEVFPEPEGRYFLLVVGLKHYMLCVLLEAGGCASKAIGSPGPDCVYVDQVKT    561 - 630
TLHQLDGVDSRIDERLASSPVPCLSCADWFLTGSREKTDSLTTSPILSRLQGTSKVATSPTCRRTLFGDY    631 - 700
SLKTRKPSPSCSSGGSDNGCEGGEDDGFSPHTTPDAVRKQRESQGSDGLEESGTLLKVTKKKSTLPNPFH    701 - 770
LGNLKKDLPEKELEIYNTVKLTSGPENTLFHYVALETVQGIFITPTLEEVAQLSGSIHPQLIKNFHQCCL    771 - 840
SIRAVFQQTLVEEKKKGLNSGDHSDSAKSVSSLNPVKEHGVLFECSPGNWTDQKKAPPVMAYWVVGRLFL    841 - 910
HPKPQELYVCFHDSVTEIAIEIAFKLFFGLTL                                          911 - 942
//

Text Mined References (13)

PMID Year Title
27158779 2016 The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery.
26644512 2015 The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells.
23186163 2013 Toward a comprehensive characterization of a human cancer cell phosphoproteome.
21948523 2011 Post-transcriptional exon shuffling events in humans can be evolutionarily conserved and abundant.
21761479 2011 PCP effector proteins inturned and fuzzy play nonredundant roles in the patterning but not convergent extension of mammalian neural tube.
16493421 2006 Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling.
16344560 2006 Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
15815621 2005 Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
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