Property Summary

NCBI Gene PubMed Count 11
Grant Count 11
Funding $1,721,328
PubMed Score 125.01
PubTator Score 17.12

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (9)

Disease log2 FC p
osteosarcoma 1.499 0.000
glioblastoma 1.600 0.028
juvenile dermatomyositis 1.161 0.000
tuberculosis -1.400 0.000
lung cancer -1.200 0.001
group 3 medulloblastoma 1.200 0.029
posterior fossa group B ependymoma 1.100 0.000
aldosterone-producing adenoma -1.284 0.013
spina bifida -1.703 0.036

Gene RIF (2)

PMID Text
19118897 studied a new FISH method to detect CHIC2 deletion, FIP1L1/PDGFRA fusion and PDGFRA translocation in patients with myeloid neoplasms associated with eosinophilia
12842979 used fluorescence in situ hybridization to detect deletion of the CHIC2 locus at 4q12 as a surrogate for the FIP1L1-PDGFRA fusion and was observed in bone marrow cells for 3 of 5 patients with systemic mast cell disease associated with eosinophilia

AA Sequence

MADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINR      1 - 70
VNSCLKKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLEWENNRLYHKLCLHWRLSKRK     71 - 140
CETNNMMEYVILIEFLPKTPIFRPD                                                 141 - 165
//

Publication (12)

PMID Year Title
25416956 2014 A proteome-scale map of the human interactome network.
21909110 2011 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
19118897 2009 Validation of a new three-color fluorescence in situ hybridization (FISH) method to detect CHIC2 deletion, FIP1L1/PDGFRA fusion and PDGFRA translocations.
19060904 2009 An empirical framework for binary interactome mapping.
16344560 2006 Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
16189514 2005 Towards a proteome-scale map of the human protein-protein interaction network.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12842979 2003 CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
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