SEPT3
Neuronal-specific septin-3
Protein Summary
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, May 2018]
- ENST00000396417
- ENSP00000379695
- ENSG00000100167
- ENST00000396425
- ENSP00000379703
- ENST00000396426
- ENSP00000379704
- SEP3
- SEP3
- bK250D10.3
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
microRNA | 0.84 | ||
molecular function | 0.76 | ||
cell type or tissue | 0.63 | ||
disease perturbation | 0.62 | ||
histone modification site profile | 0.6 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 131.93 (req: < 5)
Gene RIFs: 7 (req: <= 3)
Antibodies: 210 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 131.93 (req: >= 5)
Gene RIFs: 7 (req: > 3)
Antibodies: 210 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 7
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0