Property Summary

NCBI Gene PubMed Count 9
PubMed Score 1.83
PubTator Score 2.27

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (15)

Disease log2 FC p
astrocytoma -1.300 0.007
psoriasis -1.700 0.000
osteosarcoma -1.638 0.000
ependymoma -1.200 0.000
medulloblastoma -1.500 0.000
atypical teratoid / rhabdoid tumor -1.600 0.000
glioblastoma -1.400 0.000
medulloblastoma, large-cell -1.100 0.000
primitive neuroectodermal tumor -1.400 0.001
tuberculosis 1.100 0.000
lung cancer 1.700 0.000
pediatric high grade glioma -1.200 0.000
lung carcinoma 2.100 0.000
acute myeloid leukemia -1.200 0.030
ovarian cancer -1.600 0.000

Gene RIF (1)

PMID Text
12459492 DelGEF binds to the human homologue of Sec5 and modulates secretion.

AA Sequence

MEREPSASEAAPAAAALFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDL      1 - 70
FVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPR     71 - 140
RCVVPQAIELHKEKVVCIAAGLRHAVAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLE    141 - 210
NSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLANEAAFLPVPQKIEAHCFQNEKVTAIWSGWTHLVAQ    211 - 280
TETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPSSPHCLTGATEVSCGSEHNLAIIG    281 - 350
GVCYSWGWNEHGMCGDGTEANVWAPKPVQALLSSSGLLVGCGAGHSLALCQLPAHPALVQDPKVTYLSPD    351 - 420
AIEDTESQKAMDKERNWKERQSETSTQSQSDWSRNGGL                                    421 - 458
//

Text Mined References (11)

PMID Year Title
23455924 2013 A Y2H-seq approach defines the human protein methyltransferase interactome.
23186163 2013 Toward a comprehensive characterization of a human cancer cell phosphoproteome.
18029348 2008 Toward a confocal subcellular atlas of the human proteome.
17525332 2007 ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14980502 2004 Characterisation of an evolutionary conserved protein interacting with the putative guanine nucleotide exchange factor DelGEF and modulating secretion.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
12459492 2002 DelGEF, a homologue of the Ran guanine nucleotide exchange factor RanGEF, binds to the exocyst component Sec5 and modulates secretion.
10737800 2000 Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.
10571079 1999 DelGEF, an RCC1-related protein encoded by a gene on chromosome 11p14 critical for two forms of hereditary deafness.
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