RBPJL
Recombining binding protein suppressor of hairless-like protein
Protein Summary
Putative transcription factor, which cooperates with EBNA2 to activate transcription. This gene encodes a member of the suppressor of hairless protein family. A similar protein in mouse is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signaling pathway transcription factor recombining binding protein J. The mouse protein has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
- ENST00000343694
- ENSP00000341243
- ENSG00000124232
- ENST00000372743
- ENSP00000361828
- RBPL
- RBPSUHL
- RBPL
- SUHL
- RBPSUHL
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
protein domain | 0.73 | ||
molecular function | 0.7 | ||
gene perturbation | 0.6 | ||
biological process | 0.52 | ||
cellular component | 0.5 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 34.04 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 138 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 34.04 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 138 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 7
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0