Tbio StAR-related lipid transfer protein 9

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Microtubule-dependent motor protein required for spindle pole assembly during mitosis. Required to stabilize the pericentriolar material (PCM).

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Property Summary

NCBI Gene PubMed Count	9
PubMed Score	5.48

PubTator Score	4.78

Knowledge Summary

Patent

No data available

TINX Plot

Disease (3)

Disease	Target Count	P-value
non-small cell lung carcinoma	317	5.1e-35
lung adenocarcinoma	2716	2.2e-14
lung carcinoma	2843	7.1e-10
breast carcinoma	1638	2.7e-07
pituitary cancer	1972	4.9e-07
ductal carcinoma in situ	1745	2.4e-04
invasive ductal carcinoma	2951	6.8e-04
fibroadenoma	559	9.7e-04
group 3 medulloblastoma	4104	2.9e-02
osteosarcoma	7950	3.1e-02

Disease	Target Count	Z-score	Confidence
Carcinoma	11493	0.0	1.0
Liver cancer	604	0.0	0.5

Disease	Target Count	Z-score	Confidence
Specific language impairment	34	3.716	1.9
Autosomal recessive limb-girdle muscular dystrophy type 2A	4	3.458	1.7

Differential Expression (10)

Disease	log2 FC	p
breast carcinoma	-1.500	2.7e-07
ductal carcinoma in situ	-1.300	2.4e-04
fibroadenoma	-1.300	9.7e-04
group 3 medulloblastoma	1.300	2.9e-02
invasive ductal carcinoma	-1.500	6.8e-04
lung adenocarcinoma	-1.200	2.2e-14
lung carcinoma	-1.200	7.1e-10
non-small cell lung carcinoma	-1.600	5.1e-35
osteosarcoma	-1.219	3.1e-02
pituitary cancer	2.300	4.9e-07

Nerve - Tibial 18,007

Testis 18,518

Vagina 17,834

Uterus 17,618

Esophagus - Gastroesophageal Junction 18,000

Colon - Sigmoid 18,089

Esophagus - Muscularis 18,017

Artery - Coronary 17,949

Adipose - Subcutaneous 18,110

Ovary 17,971

Artery - Aorta 17,896

Artery - Tibial 17,631

Lung 18,057

Spleen 17,614

Breast - Mammary Tissue 18,103

Brain - Cerebellum 17,983

Brain - Cerebellar Hemisphere 18,015

Adipose - Visceral (Omentum) 17,937

Stomach 17,879

Cells - EBV-transformed lymphocytes 18,186

Prostate 18,213

Thyroid 18,024

Skin - Sun Exposed (Lower leg) 17,968

Small Intestine - Terminal Ileum 17,954

Skin - Not Sun Exposed (Suprapubic) 18,081

Brain - Spinal cord (cervical c-1) 17,973

Heart - Atrial Appendage 17,896

Minor Salivary Gland 18,005

Cells - Transformed fibroblasts 17,577

Esophagus - Mucosa 18,076

Brain - Cortex 18,039

Colon - Transverse 17,825

Brain - Caudate (basal ganglia) 18,001

Brain - Substantia nigra 17,981

Pituitary 18,147

Heart - Left Ventricle 18,006

Brain - Putamen (basal ganglia) 17,863

Brain - Frontal Cortex (BA9) 18,069

Brain - Hippocampus 18,011

Brain - Hypothalamus 18,169

Kidney - Cortex 17,329

Brain - Nucleus accumbens (basal ganglia... 18,024

Muscle - Skeletal 17,778

Brain - Amygdala 18,006

Brain - Anterior cingulate cortex (BA24) 17,989

Adrenal Gland 18,071

Whole Blood 17,439

Liver 18,071

Pancreas 18,123

Platelets 6,131

Monocytes 7,422

Adult Liver 9,113

Fetal Brain 7,866

Adult Spinal Cord 7,594

Adult Testis 10,836

NK Cells 8,475

Adult Kidney 6,723

CD8 Cells 9,840

Adult Frontal Cortex 9,048

B Cells 9,086

Adult Adrenal 8,475

Adult Lung 6,663

Adult Retina 10,115

Fetal Liver 8,402

Adult Gallbladder 7,612

Adult Pancreas 9,168

Adult Ovary 10,192

CD4 Cells 7,773

Fetal Gut 8,640

Adult Urinary Bladder 7,592

Adult Rectum 8,022

Fetal Ovary 9,118

Fetal Heart 9,228

Adult Prostate 8,952

Adrenal gland

Blood platelet

Brain

Colon

Frontal lobe

Gall bladder

Gut

Heart

Kidney

Liver

Lung

B-lymphocyte

Natural killer cell

Ovary

Pancreas

Placenta 6,083

Prostate gland

Rectum

Retina

Spinal cord

Testis

Urinary bladder

BTO:0005453

adipose tissue 15,837

adrenal gland 15,963

appendix 16,247

bone marrow 14,571

breast 16,063

cerebral cortex 16,630

cervix, uterine 15,871

colon 15,959

duodenum 15,975

endometrium 16,349

epididymis 15,863

esophagus 15,898

fallopian tube 16,245

gallbladder 16,333

heart muscle 14,972

kidney 15,917

liver 14,587

lung 16,312

lymph node 15,833

ovary 15,408

parathyroid gland 14,769

placenta 15,937

prostate 16,460

rectum 15,705

salivary gland 14,981

seminal vesicle 15,918

skeletal muscle 14,011

skin 16,206

small intestine 16,154

smooth muscle 15,857

spleen 15,972

stomach 16,099

testis 17,936

thyroid gland 15,959

tonsil 15,400

urinary bladder 15,814

Liver and Pancreas 16,750

Digestive Tract 17,369

Urinary Tract 16,678

Endocrine System 18,159

Blood and immune system 16,909

Respiratory system 16,393

Female tissues 17,400

Male tissues 17,142

Skin and soft tissues 17,230

Nervous System 16,725

Cardiovascular System 15,192

Brain 7,346

Testis 3,897

Thymus 427

Uterine cervix 418

Pronephros 717

See source...

Synonym

Accession	Q9P2P6 Q68DG2 Q6AI01 Q6ZWK0 Q9UF70
Symbols	KIF16A

Gene

STARD9

Ortholog (6)

Species	Source	Disease
Opossum 12,230	Inparanoid EggNOG
Anole lizard 10,588	Inparanoid OMA EggNOG
Rat 15,117	OMA EggNOG
Dog 15,073	Inparanoid OMA EggNOG
Chimp 14,140	OMA EggNOG
Mouse 16,570	Inparanoid OMA EggNOG

UniProt Keyword (12)

Complete proteome 20,231

Nucleus 5,259

Polymorphism 12,194

Reference proteome 20,231

Alternative splicing 10,528

Cytoplasm 4,952

Cytoskeleton 1,182

Phosphoprotein 8,216

ATP-binding 1,380

Coiled coil 2,153

See all...

GO Function (4)

ATP binding 1,477

microtubule binding 212

microtubule motor activity 61

cholesterol binding 44

GO Component (3)

nucleus 5,097

centriole 124

cytoplasm 4,094

GO Process (3)

spindle assembly 25

microtubule-based movement 72

metabolic process 43

Compartment GO Term (25)

Cell 16,178

Cell part 16,177

Centriole 134

Centrosome 696

Cytoplasm 10,983

Cytoplasmic part 9,247

Cytoskeletal part 1,637

Cytoskeleton 2,108

Intracellular 14,109

Intracellular membrane-bounded organelle 10,341

Intracellular non-membrane-bounded organ... 3,975

Intracellular organelle 12,025

Intracellular organelle part 8,783

Intracellular part 13,972

Kinesin complex 70

See all...

GWAS Trait (2)

Protein quantitative trait loci 31

Coronary artery calcified atheroscleroti... 44

HCA RNA Cell Line (56)

A-431 16,131

A549 15,174

AF22 16,160

AN3-CA 15,648

ASC TERT1 14,842

BEWO 16,726

BJ 15,448

BJ hTERT+ 15,353

BJ hTERT+ SV40 Large T+ 15,609

BJ hTERT+ SV40 Large T+ RasG12V 15,493

See all...

Gene RIF (4)

AA Sequence

MANVQVAVRVRPLSKRETKEGGRIIVEVDGKVAKIRNLKVDNRPDGFGDSREKVMAFGFDYCYWSVNPED      1 - 70
PQYASQDVVFQDLGMEVLSGVAKGYNICLFAYGQTGSGKTYTMLGTPASVGLTPRICEGLFVREKDCASL     71 - 140
PSSCRIKVSFLEIYNERVRDLLKQSGQKKSYTLRVREHPEMGPYVQGLSQHVVTNYKQVIQLLEEGIANR    141 - 210
ITAATHVHEASSRSHAIFTIHYTQAILENNLPSEMASKINLVDLAGSERADPSYCKDRIAEGANINKSLV    211 - 280
TLGIVISTLAQNSQVFSSCQSLNSSVSNGGDSGILSSPSGTSSGGAPSRRQSYIPYRDSVLTWLLKDSLG    281 - 350
GNSKTIMVATVSPAHTSYSETMSTLRYASSAKNIINKPRVNEDANLKLIRELREEIERLKALLLSFELRN    351 - 420
FSSLSDENLKELVLQNELKIDQLTKDWTQKWNDWQALMEHYSVDINRRRAGVVIDSSLPHLMALEDDVLS    421 - 490
TGVVLYHLKEGTTKIGRIDSDQEQDIVLQGQWIERDHCTITSACGVVVLRPARGARCTVNGREVTASCRL    491 - 560
TQGAVITLGKAQKFRFNHPAEAAVLRQRRQVGEAAAGRGSLEWLDLDGDLAASRLGLSPLLWKERRALEE    561 - 630
QCDEDHQTPRDGETSHRAQIQQQQSYVEDLRHQILAEEIRAAKELEFDQAWISQQIKENQQCLLREETWL    631 - 700
ASLQQQQQEDQVAEKELEASVALDAWLQTDPEIQPSPFVQSQKRVVHLQLLRRHTLRAAERNVRRKKVSF    701 - 770
QLERIIKKQRLLEAQKRLEKLTTLCWLQDDSTQEPPYQVLSPDATVPRPPCRSKLTSCSSLSPQRLCSKH    771 - 840
MPQLHSIFLSWDPSTTLPPRPDPTHQTSEKTSSEEHLPQAASYPARTGCLRKNGLHSSGHGQPCTARAAL    841 - 910
ARKGASAPDACLTMSPNSVGIQEMEMGVKQPHQMVSQGLASLRKSANKLKPRHEPKIFTSTTQTRGAKGL    911 - 980
ADPSHTQAGWRKEGNLGTHKAAKGASCNSLYPHGPRQTAGHGKAVKTFWTEYKPPSPSRASKRHQRVLAT    981 - 1050
RVRNITKKSSHLPLGSPLKRQQNTRDPDTMVPLTDFSPVMDHSREKDNDLSDTDSNYSLDSLSCVYAKAL   1051 - 1120
IEPLKPEERKWDFPEPENSESDDSQLSEDSLAEKRYQSPKNRLGGNRPTNNRGQPRTRTRASVRGFTAAS   1121 - 1190
DSDLLAQTHRSFSLDSLIDAEEELGEDQQEEPFPGSADEIPTETFWHLEDSSLPVMDQEAICRLGPINYR   1191 - 1260
TAARLDAVLPMSSSFYLDPQFQPHCELQPHCELQPHCELQPHCEQAESQVEPSYSEQADSLQGMQLSRES   1261 - 1330
PLMSMDSWFSCDSKINPSSPPGIVGSLCPSPDMQEFHSCKGERPGYWPNTEELKPSDAETVLPYSSKLHQ   1331 - 1400
GSTELLCSARDEHTASAADTSRLSLWGIQRLIQPGADGTFQGRCIPDMTQQGSSEASHNSSVSNVLAASA   1401 - 1470
TTLTHVGSTHERDWSALQQKYLLELSCPVLEAIGAPKPAYPYLEEDSGSLAQASSKGGDTLLPVGPRVSS   1471 - 1540
NLNLNNFPVHLSRIRRLRAEKEQDSLNAKLEGVSDFFSTSEKEASYDETYSADLESLSASRSTNAQVFAT   1541 - 1610
ENAIPDSMTEACEVKQNNLEECLQSCRKPGLMTSSDEDFFQKNACHSNVTTATKADHWSQGWAPLRKNSA   1611 - 1680
VQPGQLSPDSHYPLEEEKTDCQESSKEAVRRHINVSFALPSGPELYLHSAPWNPLSSSLQPPLLETFYVT   1681 - 1750
KSRDALTETALEIPACREVRVPSPPPREAWGFGHNHQALQGAYLKNNLPVLLQNQNSKIASSQQVTAEIP   1751 - 1820
VDLNTREVIRESGKCPGNITEESHDSVYSSVTQNRHFLPSTSTKVCEFENQVVILNKKHSFPALEGGEVT   1821 - 1890
AQSCCGASSDSTESGKSLLFRESEAREEEELDQNTVLRQTINVSLEKDMPGESAVSLKSRSVDRRVSSPV   1891 - 1960
MVAQGGGPTPKWEGKNETGLLEKGLRPKDSSEEFKLPGTKPAYERFQLVACPQERNPSECKSQEMLNPNR   1961 - 2030
EPSGKKQNKRVNNTDEMARLIRSVMQLENGILEIESKQNKQVHASHTPGTDKELVFQDQKEQEKTDHAFR   2031 - 2100
PDSSGNPLPSKDQPSSPRQTDDTVFRDSEAGAMEVNSIGNHPQVQKITPNPFRSREGVRESEPVREHTHP   2101 - 2170
AGSDRPARDICDSLGKHTTCREFTNTSLHPQRMKALARALPLQPRLERSSKNNGQFVKASASLKGQPWGL   2171 - 2240
GSLEELETVKGFQESQVAEHVSSSNQEEPKAQGKVEEMPMQRGGSLQEENKVTQKFPSLSQLCRDTFFRQ   2241 - 2310
ETVSPLLSRTEFCTAPLHQDLSNTLPLNSPRWPRRCLHVPVALGISSLDCVLDLTMLKIHNSPLVTGVEH   2311 - 2380
QDQSTETRSHSPEGNVRGRSSEAHTAWCGSVRSMAMGSHSQSGVPESIPLGTEDRISASTSPQDHGKDLR   2381 - 2450
ITLLGFSTSEDFASEAEVAVQKEIRVSSLNKVSSQPEKRVSFSLEEDSDQASKPRQKAEKETEDVGLTSG   2451 - 2520
VSLAPVSLPRVPSPEPRLLEPSDHASMCLAILEEIRQAKAQRKQLHDFVARGTVLSYCETLLEPECSSRV   2521 - 2590
AGRPQCKQIDQSSSDQTRNEGEAPGFHVASLSAEAGQIDLLPDERKVQATSLSADSFESLPNTETDREPW   2591 - 2660
DPVQAFSHAAPAQDRKRRTGELRQFAGASEPFICHSSSSEIIEKKKDATRTPSSADPLAPDSPRSSAPVE   2661 - 2730
EVRRVVSKKVVAALPSQAPYDDPRVTLHELSQSVPQETAEGIPPGSQDSSPEHQEPRTLDTTYGEVSDNL   2731 - 2800
LVTAQGEKTAHFESQSVTCDVQNSTSASGPKQDHVQCPEASTGFEEGRASPKQDTILPGALTRVALEAPT   2801 - 2870
QQCVQCKESVGSGLTEVCRAGSKHSRPIPLPDQRPSANPGGIGEEAPCRHPREALDGPVFSRNPEGSRTL   2871 - 2940
SPSRGKESRTLPCRQPCSSQPVATHAYSSHSSTLLCFRDGDLGKEPFKAAPHTIHPPCVVPSRAYEMDET   2941 - 3010
GEISRGPDVHLTHGLEPKDVNREFRLTESSTCEPSTVAAVLSRAQGCRSPSAPDVRTGSFSHSATDGSVG   3011 - 3080
LIGVPEKKVAEKQASTELEAASFPAGMYSEPLRQFRDSSVGDQNAQVCQTNPEPPATTQGPHTLDLSEGS   3081 - 3150
AESKLVVEPQHECLENTTRCFLEKPQFSTELRDHNRLDSQAKFVARLKHTCSPQEDSPWQEEEQHRDQAS   3151 - 3220
GGGEGFAQGVNPLPDEDGLDGCQILDAGREEVAVAKPPVSKILSQGFKDPATVSLRQNETPQPAAQRSGH   3221 - 3290
LYTGREQPAPNHRGSLPVTTIFSGPKHSRSSPTPQFSVVGSSRSLQELNLSVEPPSPTDEDTQGPNRLWN   3291 - 3360
PHLRGYSSGKSVARTSLQAEDSNQKASSRLDDGTTDHRHLKPATPPYPMPSTLSHMPTPDFTTSWMSGTL   3361 - 3430
EQAQQGKREKLGVQVRPENWCSQMDKGMLHFGSSDISPYALPWRPEEPARISWKQYMSGSAVDVSCSQKP   3431 - 3500
QGLTLSNVARCSSMDNGLEDQNSPFHSHLSTYANICDLSTTHSSTENAQGSNEAWEVFRGSSSIALGDPH   3501 - 3570
IPTSPEGVAPTSGHDRRPQFRGPSGEADCLRSKPPLAKGSAAGPVDEIMLLYPSEAGCPVGQTRTNTFEQ   3571 - 3640
GTQTLGSRRHWSSTDISFAQPEASAVSAFDLASWTSMHNLSLHLSQLLHSTSELLGSLSQPDVARREQNT   3641 - 3710
KRDIPDKAPQALMMDGSTQTTVDEGSQTDLTLPTLCLQTSEAEPQGANVILEGLGSDTSTVSQEEGDVPG   3711 - 3780
VPQKREAEETAQKMAQLLYLQEESTPYKPQSPSIPSSHLRFQKAPVGQHLPSVSPSVSDAFLPPSSQPEE   3781 - 3850
SYCLVVSSPSPSSPHSPGLFPSTSEYPGDSRVQKKLGPTSALFVDRASSPILTLSASTQEPGLSPGSLTL   3851 - 3920
SAPSTHPVEGHQKLDSSPDPVDAPRTPMDNYSQTTDELGGSQRGRSSLQRSNGRSFLELHSPHSPQQSPK   3921 - 3990
LQFSFLGQHPQQLQPRTTIGVQSRLLPPPLRHRSQRLGNSFVPEKVASPEHCPLSGREPSQWQSRTENGG   3991 - 4060
ESSASPGEPQRTLDRPSSWGGLQHLSPCPVSELTDTAGLRGSALGLPQACQPEELLCFSCQMCMAPEHQH   4061 - 4130
HSLRDLPVHNKFSNWCGVQKGSPGGLDMTEEELGASGDLSSEKQEQSPPQPPNDHSQDSEWSKREQIPLQ   4131 - 4200
VGAQNLSLSVELTEAKLHHGFGEADALLQVLQSGTGEALAADEPVTSTWKELYARQKKAIETLRRERAER   4201 - 4270
LGNFCRTRSLSPQKQLSLLPNKDLFIWDLDLPSRRREYLQQLRKDVVETTRSPESVSRSAHTPSDIELML   4271 - 4340
QDYQQAHEEAKVEIARARDQLRERTEQEKLRIHQKIISQLLKEEDKLHTLANSSSLCTSSNGSLSSGMTS   4341 - 4410
GYNSSPALSGQLQFPENMGHTNLPDSRDVWIGDERGGHSAVRKNSAYSHRASLGSCCCSPSSLSSLGTCF   4411 - 4480
SSSYQDLAKHVVDTSMADVMAACSDNLHNLFSCQATAGWNYQGEEQAVQLYYKVFSPTRHGFLGAGVVSQ   4481 - 4550
PLSRVWAAVSDPTVWPLYYKPIQTARLHQRVTNSISLVYLVCNTTLCALKQPRDFCCVCVEAKEGHLSVM   4551 - 4620
AAQSVYDTSMPRPSRKMVRGEILPSAWILQPITVEGKEVTRVIYLAQVELGAPGFPPQLLSSFIKRQPLV   4621 - 4690
IARLASFLGR                                                               4691 - 4700
//

Text Mined References (13)

Summary
Details

	PMID	Year	Title

Tbio StAR-related lipid transfer protein 9 Add to cart View Collections Empty Collection

Property Summary

Knowledge Summary

Patent

No data available

TINX Plot

Disease (3)

Expression

Differential Expression (10)

Synonym

Gene

Ortholog (6)

UniProt Keyword (12)

GO Function (4)

GO Component (3)

GO Process (3)

Compartment GO Term (25)

GWAS Trait (2)

HCA RNA Cell Line (56)

Gene RIF (4)

AA Sequence

Text Mined References (13)

Tbio StAR-related lipid transfer protein 9

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