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Tbio
CHD7
Chromodomain-helicase-DNA-binding protein 7

Protein Summary
Description
Probable transcription regulator. Maybe involved in the in 45S precursor rRNA production. This gene encodes a protein that contains several helicase family domains. Mutations in this gene have been found in some patients with the CHARGE syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000423902
  • ENSP00000392028
  • ENSG00000171316
  • ENST00000524602
  • ENSP00000437061
  • ENST00000525508
  • ENSP00000436027

Symbol
  • KIAA1416
  • CRG
  • HH5
  • IS3
  • KAL5
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.99
molecular function
0.96
biological process
0.95
virus perturbation
0.9
microRNA
0.87


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1756.7   (req: < 5)
Gene RIFs: 111   (req: <= 3)
Antibodies: 132   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1756.7   (req: >= 5)
Gene RIFs: 111   (req: > 3)
Antibodies: 132   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 46
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0