Tbio SLAIN2 SLAIN motif-containing protein 2

Protein Summary

Description

Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Required for normal structure of the microtubule cytoskeleton during interphase.

Uniprot Accession IDs

• Q9P270
• A8K4P1
• Q8N5R3

Gene Name

• SLAIN2

Ensembl ID

• ENST00000264313
• ENSP00000264313
• ENSG00000109171

Symbol

• KIAA1458
• KIAA1458

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.88
transcription factor binding site profile	0.81
virus perturbation	0.76
histone modification site profile	0.7
cell type or tissue	0.67

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.05   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 103   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.05   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 103   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0