Property Summary

NCBI Gene PubMed Count 15
Grant Count 2
R01 Count 2
Funding $192,346.5
PubMed Score 9.59
PubTator Score 2.56

Knowledge Summary

Patent

No data available

Expression

Synonym

Accession Q9P055 B4DP67 Q6FIB6 Q6IAJ2 Q7Z5D4 Q86SY6 Q9H0Q6 Q9H2W0 Q9HAH5 Q9P0R3 JKAMP
Symbols JAMP
CDA06
HSPC213
HSPC327
C14orf100

Gene

 Grant Application (2)

Gene RIF (6)

PMID Text
25173965 synergistic function of Jnk1 in haematopoietic cells and hepatocytes might be relevant for the development of chronic liver injury
23798571 Expression of DP, a receptor largely retained in the ER, promoted proteasome recruitment by JAMP.
20379614 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
19269966 RNF5 associates with JAMP in the ER membrane. This association results in Ubc13-dependent RNF5-mediated noncanonical ubiquitination of JAMP.
18784250 JAMP is an important component for coordinated clearance of misfolded proteins from the endoplasmic reticulum.
16166642 Identification and functional characterization of the mouse Jamp ortholog.

AA Sequence

MFGAAARSADLALLEKNLQAAHGCLGLYCGKTLLFKNGSTEIYGECGVCPRGQRTNAQKYCQPCTESPEL      1 - 70
YDWLYLGFMAMLPLVLHWFFIEWYSGKKSSSALFQHITALFECSMAAIITLLVSDPVGVLYIRSCRVLML     71 - 140
SDWYTMLYNPSPDYVTTVHCTHEAVYPLYTIVFIYYAFCLVLMMLLRPLLVKKIACGLGKSDRFKSIYAA    141 - 210
LYFFPILTVLQAVGGGLLYYAFPYIILVLSLVTLAVYMSASEIENCYDLLVRKKRLIVLFSHWLLHAYGI    211 - 280
ISISRVDKLEQDLPLLALVPTPALFYLFTAKFTEPSRILSEGANGH                            281 - 326
//

Text Mined References (15)

PMID Year Title
25173965 2015 Haematopoietic cell-derived Jnk1 is crucial for chronic inflammation and carcinogenesis in an experimental model of liver injury.
23798571 2013 Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability.
20379614 Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
19269966 2009 Regulation of endoplasmic reticulum-associated degradation by RNF5-dependent ubiquitination of JNK-associated membrane protein (JAMP).
18784250 2008 JAMP optimizes ERAD to protect cells from unfolded proteins.
16381901 2006 The LIFEdb database in 2006.
16166642 2005 JAMP, a Jun N-terminal kinase 1 (JNK1)-associated membrane protein, regulates duration of JNK activity.
15489336 2004 From ORFeome to biology: a functional genomics pipeline.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
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