Property Summary

NCBI Gene PubMed Count 11
PubMed Score 4.89
PubTator Score 2.50

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (3)

Disease Target Count P-value
breast carcinoma 1614 2.41206432176453E-23
posterior fossa group B ependymoma 1530 5.20775234026038E-8
tuberculosis and treatment for 3 months 327 7.32564588850291E-7
ovarian cancer 8492 1.35063779679693E-5
atypical teratoid / rhabdoid tumor 4369 0.00125427838950397
hepatocellular carcinoma 550 0.00147417362850632
nasopharyngeal carcinoma 1056 0.00206887366484903
intraductal papillary-mucinous adenoma (IPMA) 2956 0.00217845185656301
intraductal papillary-mucinous carcinoma (IPMC) 2988 0.00347575979928712
medulloblastoma, large-cell 6234 0.00580627618692569
ductal carcinoma in situ 1745 0.00776734147160995
intraductal papillary-mucinous neoplasm (IPMN) 3289 0.0109308836046993
osteosarcoma 7933 0.0168228996749672
Breast cancer 3099 0.0260219833290876
subependymal giant cell astrocytoma 2287 0.028818377689795
lung cancer 4473 0.0316365839385954
Disease Target Count Z-score Confidence
Kidney disease 397 0.0 1.0
Disease Target Count
Loeys-Dietz syndrome 4 4

Expression

Synonym

Accession Q9NW75 Q5VYK7 Q5VYK8 Q86YE7
Symbols CT110
GPATC2
PPP1R30

Gene

PANTHER Protein Class (1)

  Ortholog (10)

Species Source
Chimp OMA EggNOG
Macaque OMA EggNOG Inparanoid
Mouse OMA Inparanoid
Dog OMA EggNOG Inparanoid
Cow OMA Inparanoid
Opossum OMA EggNOG Inparanoid
Platypus OMA EggNOG Inparanoid
Chicken OMA EggNOG Inparanoid
Anole lizard OMA Inparanoid
Xenopus OMA EggNOG Inparanoid

Gene RIF (3)

PMID Text
25376275 GPATC2 may be involved in inhibiting G1-S phase transition in 293T cells.
20379614 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
19432882 Involvement of GPATCH2 overexpression in breast carcinogensis is reported.

AA Sequence

MFGAAGRQPIGAPAAGNSWHFSRTMEELVHDLVSALEESSEQARGGFAETGDHSRSISCPLKRQARKRRG      1 - 70
RKRRSYNVHHPWETGHCLSEGSDSSLEEPSKDYRENHNNNKKDHSDSDDQMLVAKRRPSSNLNNNVRGKR     71 - 140
PLWHESDFAVDNVGNRTLRRRRKVKRMAVDLPQDISNKRTMTQPPEGCRDQDMDSDRAYQYQEFTKNKVK    141 - 210
KRKLKIIRQGPKIQDEGVVLESEETNQTNKDKMECEEQKVSDELMSESDSSSLSSTDAGLFTNDEGRQGD    211 - 280
DEQSDWFYEKESGGACGITGVVPWWEKEDPTELDKNVPDPVFESILTGSFPLMSHPSRRGFQARLSRLHG    281 - 350
MSSKNIKKSGGTPTSMVPIPGPVGNKRMVHFSPDSHHHDHWFSPGARTEHDQHQLLRDNRAERGHKKNCS    351 - 420
VRTASRQTSMHLGSLCTGDIKRRRKAAPLPGPTTAGFVGENAQPILENNIGNRMLQNMGWTPGSGLGRDG    421 - 490
KGISEPIQAMQRPKGLGLGFPLPKSTSATTTPNAGKSA                                    491 - 528
//

Text Mined References (17)

PMID Year Title
25376275 2015 G-patch domain containing 2, a gene highly expressed in testes, inhibits nuclear factor-?B and cell proliferation.
23186163 2013 Toward a comprehensive characterization of a human cancer cell phosphoproteome.
22589738 2012 Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.
21546767 2011 Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes.
21406692 2011 System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
20379614 Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
20068231 2010 Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
19690332 2009 Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
19432882 2009 Involvement of G-patch domain containing 2 overexpression in breast carcinogenesis.
19389623 2009 Docking motif-guided mapping of the interactome of protein phosphatase-1.
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