| Tdark | Protein SDA1 homolog |
Required for 60S pre-ribosomal subunits export to the cytoplasm.
Comments
| Disease | Target Count | P-value |
|---|---|---|
| juvenile dermatomyositis | 1187 | 5.3e-10 |
| ovarian cancer | 8520 | 6.6e-06 |
| ulcerative colitis | 1819 | 2.2e-05 |
| psoriasis | 6694 | 4.1e-05 |
| Pick disease | 1894 | 8.9e-05 |
| atypical teratoid / rhabdoid tumor | 5112 | 2.4e-04 |
| osteosarcoma | 7950 | 8.9e-04 |
| medulloblastoma, large-cell | 6241 | 1.8e-03 |
| adult high grade glioma | 3801 | 7.4e-03 |
| glioblastoma | 5792 | 1.2e-02 |
| colon cancer | 1478 | 1.5e-02 |
| Gaucher disease type 1 | 180 | 1.8e-02 |
| Breast cancer | 3578 | 2.7e-02 |
| Disease | log2 FC | p |
|---|---|---|
| adult high grade glioma | -1.200 | 7.4e-03 |
| atypical teratoid / rhabdoid tumor | -1.600 | 2.4e-04 |
| Breast cancer | 2.400 | 2.7e-02 |
| colon cancer | 1.600 | 1.5e-02 |
| Gaucher disease type 1 | 1.100 | 1.8e-02 |
| glioblastoma | -1.200 | 1.2e-02 |
| juvenile dermatomyositis | 1.255 | 5.3e-10 |
| medulloblastoma, large-cell | -1.300 | 1.8e-03 |
| osteosarcoma | 1.146 | 8.9e-04 |
| ovarian cancer | -1.100 | 6.6e-06 |
| Pick disease | -1.100 | 8.9e-05 |
| psoriasis | -2.500 | 4.1e-05 |
| ulcerative colitis | 1.100 | 2.2e-05 |
MSNRNNNKLPSNLPQLQNLIKRDPPAYIEEFLQQYNHYKSNVEIFKLQPNKPSKELAELVMFMAQISHCY 1 - 70 PEYLSNFPQEVKDLLSCNHTVLDPDLRMTFCKALILLRNKNLINPSSLLELFFELFRCHDKLLRKTLYTH 71 - 140 IVTDIKNINAKHKNNKVNVVLQNFMYTMLRDSNATAAKMSLDVMIELYRRNIWNDAKTVNVITTACFSKV 141 - 210 TKILVAALTFFLGKDEDEKQDSDSESEDDGPTARDLLVQYATGKKSSKNKKKLEKAMKVLKKQKKKKKPE 211 - 280 VFNFSAIHLIHDPQDFAEKLLKQLECCKERFEVKMMLMNLISRLVGIHELFLFNFYPFLQRFLQPHQREV 281 - 350 TKILLFAAQASHHLVPPEIIQSLLMTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQY 351 - 420 KTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPTEASIEARVQEYGELDAKDYIPGAEVLEVEKEENA 421 - 490 ENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERKAKAAAISTSRVLTQEDFQKIR 491 - 560 MAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRK 561 - 630 KTKTNPFSSSTNKEKKKQKNFMMMRYSQNVRSKNKRSFREKQLALRDALLKKRKRMK 631 - 687 //
