Property Summary

NCBI Gene PubMed Count 13
PubMed Score 7.27
PubTator Score 4.19

Knowledge Summary


No data available


  Disease Sources (3)

Disease Target Count
IGA Glomerulonephritis 454
Disease Target Count P-value
non-small cell lung cancer 2798 4.78764315435657E-30
lung adenocarcinoma 2714 2.49019247464485E-25
lung carcinoma 2844 4.03482513574367E-16
lung cancer 4473 2.59050910056631E-8
pituitary cancer 1972 2.31780021722352E-7
pilocytic astrocytoma 3086 2.77401802968734E-7
breast carcinoma 1614 5.78033961127813E-6
medulloblastoma, large-cell 6234 7.65068984872314E-6
colon cancer 1475 1.39437438701485E-5
glioblastoma 5572 2.19554847841295E-4
invasive ductal carcinoma 2950 2.45861848050757E-4
adult high grade glioma 2148 2.56181308018393E-4
intraductal papillary-mucinous carcinoma (IPMC) 2988 8.03966091243451E-4
ductal carcinoma in situ 1745 0.00100358784412847
atypical teratoid / rhabdoid tumor 4369 0.00167447027393963
intraductal papillary-mucinous adenoma (IPMA) 2956 0.00182792791554121
intraductal papillary-mucinous neoplasm (IPMN) 3289 0.0026275309252178
Atopic dermatitis 944 0.00682482552356088
fibroadenoma 557 0.00829248212811618
oligodendroglioma 2849 0.0139981121497892
cutaneous lupus erythematosus 1056 0.0175932290948298
astrocytic glioma 2241 0.0300426699934347
adrenocortical carcinoma 1427 0.0433477295392732
medulloblastoma 1524 0.044395371485691
Disease Target Count Z-score Confidence
Telangiectasis 20 3.713 1.9



Accession Q9NV29 D3DTY7 I3L214 Q96FZ0


  Ortholog (12)

Pathway (1)

Gene RIF (4)

25978032 The current findings suggest that TMEM100 functions as a tumor suppressor in hepatocellular carcinoma metastasis and proliferation.
23485812 This study demonistrated that TMEM100 is a novel, membrane-associated marker for enteric nerves and is as effective as PGP9.5 for identifying neuronal structures in the gastrointestinal tract.
22223368 Loss of TMEM100 is associated with lung adenocarcinoma.
19058789 Observational study of gene-disease association. (HuGE Navigator)

AA Sequence


Text Mined References (14)

PMID Year Title
25978032 2015 Novel roles of TMEM100: inhibition metastasis and proliferation of hepatocellular carcinoma.
25640077 2015 Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain.
25416956 2014 A proteome-scale map of the human interactome network.
23485812 2013 Distribution of TMEM100 in the mouse and human gastrointestinal tract--a novel marker of enteric nerves.
22783020 2012 Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis.
22223368 2012 Association of lung adenocarcinoma clinical stage with gene expression pattern in noninvolved lung tissue.
22021425 2012 Genome-wide association study of body height in African Americans: the Women's Health Initiative SNP Health Association Resource (SHARe).
19058789 2009 A common variant in DRD3 receptor is associated with autism spectrum disorder.
16712791 2006 Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags.
16625196 2006 DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.