Property Summary

NCBI Gene PubMed Count 16
PubMed Score 4.42
PubTator Score 2.29

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (3)

Disease Target Count P-value
lung carcinoma 2844 4.734220725875E-28
oligodendroglioma 2849 9.70051190713867E-13
posterior fossa group A ependymoma 1511 7.6772503727995E-8
juvenile dermatomyositis 1189 2.59967343365345E-7
malignant mesothelioma 3163 1.46403888869282E-6
primitive neuroectodermal tumor 3031 2.16762870270676E-5
sonic hedgehog group medulloblastoma 1482 2.30473806102466E-5
glioblastoma 5572 2.48906941080115E-5
tuberculosis 1563 4.31690204749507E-5
pilocytic astrocytoma 3086 8.17288397175493E-5
pediatric high grade glioma 2712 8.49544851867092E-5
lung cancer 4473 9.94069437761669E-5
acute quadriplegic myopathy 1157 2.28781865473135E-4
medulloblastoma, large-cell 6234 3.56549111516499E-4
psoriasis 6685 8.00145956612771E-4
dermatomyositis 967 0.00175479824693669
Waldenstrons macroglobulinemia 765 0.00379593012355413
primary Sjogren syndrome 789 0.0046810467122526
chronic lymphocytic leukemia 244 0.00505696088884412
ductal carcinoma in situ 1745 0.00611706987148935
osteosarcoma 7933 0.0282928693896118
astrocytic glioma 2241 0.0397599220738783
Disease Target Count Z-score Confidence
Rheumatoid Arthritis 1171 0.0 2.0
Disease Target Count Z-score Confidence
estrogen-receptor positive breast cancer 7 3.261 1.6

Expression

  Differential Expression (22)

Synonym

Accession Q9NUQ2 Q8IZ47 Q9BQG4
Symbols LPAATE
1AGPAT5

Gene

  Ortholog (12)

Gene RIF (4)

PMID Text
21173190 enzymatic properties, tissue distribution, and subcellular localization of human AGPAT3 and AGPAT5
20877624 Observational study of gene-disease association. (HuGE Navigator)
20379614 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
15367102 This publication describes the molecular cloning, tissue distribution, and enzyme characterization of the mouse homolog, mAGPAT5.

AA Sequence

MLLSLVLHTYSMRYLLPSVVLLGTAPTYVLAWGVWRLLSAFLPARFYQALDDRLYCVYQSMVLFFFENYT      1 - 70
GVQILLYGDLPKNKENIIYLANHQSTVDWIVADILAIRQNALGHVRYVLKEGLKWLPLYGCYFAQHGGIY     71 - 140
VKRSAKFNEKEMRNKLQSYVDAGTPMYLVIFPEGTRYNPEQTKVLSASQAFAAQRGLAVLKHVLTPRIKA    141 - 210
THVAFDCMKNYLDAIYDVTVVYEGKDDGGQRRESPTMTEFLCKECPKIHIHIDRIDKKDVPEEQEHMRRW    211 - 280
LHERFEIKDKMLIEFYESPDPERRKRFPGKSVNSKLSIKKTLPSMLILSGLTAGMLMTDAGRKLYVNTWI    281 - 350
YGTLLGCLWVTIKA                                                            351 - 364
//

Text Mined References (18)

PMID Year Title
25944712 2015 N-terminome analysis of the human mitochondrial proteome.
25416956 2014 A proteome-scale map of the human interactome network.
21269460 2011 Initial characterization of the human central proteome.
21173190 2011 Enzymatic activities of the human AGPAT isoform 3 and isoform 5: localization of AGPAT5 to mitochondria.
20877624 2010 Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
20379614 Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
16620771 2006 Functional characterization of human 1-acylglycerol-3-phosphate acyltransferase isoform 8: cloning, tissue distribution, gene structure, and enzymatic activity.
16381901 2006 The LIFEdb database in 2006.
16341674 2005 Transcriptome analysis of human gastric cancer.
15489336 2004 From ORFeome to biology: a functional genomics pipeline.
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