Property Summary

NCBI Gene PubMed Count 7
PubMed Score 6.35
PubTator Score 3.35

Knowledge Summary


No data available


  Disease Sources (2)

Disease Target Count P-value
posterior fossa group A ependymoma 1511 3.43425258637245E-13
atypical teratoid/rhabdoid tumor 1095 2.31064570299229E-9
sonic hedgehog group medulloblastoma 1482 1.18533644773925E-8
glioblastoma 5572 3.20708450342415E-7
pediatric high grade glioma 2712 9.31053610483681E-7
medulloblastoma, large-cell 6234 1.65286185096847E-5
osteosarcoma 7933 8.87185630374854E-5
ovarian cancer 8492 5.63837367279507E-4
acute myeloid leukemia 785 0.00259667591510645
pancreatic ductal adenocarcinoma liver metastasis 1795 0.0178363015777467
Disease Target Count Z-score Confidence
Chondrodysplasia punctata 41 4.019 2.0
Pollen allergy 6 3.877 1.9



Accession Q9NRP0 A8MYS2 B2R5H1 D6RH22 Q9P075 Q9P1R4
Symbols DC2


  Ortholog (13)

Gene RIF (2)

24751383 These results suggest that the upregulation of OSTC/DC2, a novel component of the oligosaccharyltransferase complex, is part of the mammalian heat shock response.
20332099 Observational study of gene-disease association. (HuGE Navigator)

AA Sequence

MKLPGYLMG                                                                 141 - 149

Text Mined References (13)

PMID Year Title
25944712 2015 N-terminome analysis of the human mitochondrial proteome.
25416956 2014 A proteome-scale map of the human interactome network.
24751383 2014 Heat shock induces expression of OSTC/DC2, a novel subunit of oligosaccharyltransferase, in vitro and in vivo.
21269460 2011 Initial characterization of the human central proteome.
20332099 2010 A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.
16959974 2006 The consensus coding sequences of human breast and colorectal cancers.
16712791 2006 Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags.
15835887 2005 Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits.
15815621 2005 Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).